Understanding the chemical nature and synthesis of pharmaceutical compounds is fundamental to their development and application. Buflomedil Hydrochloride, a significant vasodilator, possesses a distinct chemical structure that underpins its pharmacological activity. The reliable synthesis of this compound is crucial for its availability in research and clinical settings. NINGBO INNO PHARMCHEM CO.,LTD. plays a key role in providing consistent access to high-quality Buflomedil Hydrochloride.

The chemical name for Buflomedil Hydrochloride is 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride. Its molecular formula is C17H26ClNO4, and it has a molecular weight of approximately 343.85 g/mol. Typically appearing as a white or off-white crystalline powder, its physical state and purity are critical parameters for its intended use. The compound's solubility characteristics, often tested in solvents like DMSO, ethanol, and water, are also important for formulation and experimental procedures.

The synthesis of Buflomedil Hydrochloride often involves chemical reactions that assemble its complex molecular structure. One described method involves the acylation between 1,3,5-trimethoxybenzene and 4-pyrrolidinobutyronitrile in a suitable solvent, often in the presence of hydrochloric acid, employing principles similar to the Hoesch reaction. This process requires precise control over reaction conditions, purification techniques, and quality assurance to yield a product that meets stringent pharmaceutical standards. Ensuring the enantiomeric purity and absence of critical impurities are key aspects of its manufacturing.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier of pharmaceutical raw materials, including Buflomedil Hydrochloride. By adhering to strict quality control measures and employing advanced synthetic methodologies, the company ensures that the Buflomedil Hydrochloride provided meets the high standards required for pharmaceutical research and development. The availability of well-characterized and high-purity compounds like Buflomedil Hydrochloride is essential for advancing our understanding of cardiovascular physiology and developing new therapeutic interventions. The chemical profile and synthesis efficiency directly impact its utility and accessibility for scientific exploration.