Nitrofurazone, identified by the CAS number 59-87-0, is a synthetic antimicrobial belonging to the nitrofuran class. Its chemical structure, C6H6N4O4, is characterized by a furan ring substituted with a nitro group and a semicarbazone moiety. This unique arrangement dictates its chemical properties and biological activity, making it a compound of interest in various scientific and industrial applications. NINGBO INNO PHARMCHEM CO.,LTD. provides insight into these critical chemical aspects.

Physically, nitrofurazone typically presents as a pale yellow to yellow crystalline powder. It exhibits limited solubility in water but is slightly soluble in ethanol, especially when heated. Its melting point is generally reported around 240-244°C with decomposition, a key identifier in its characterization. Understanding these nitrofurazone chemical properties is fundamental for anyone considering its use in formulations or laboratory experiments.

The synthesis of nitrofurazone typically involves the condensation reaction between 5-nitrofurfural and semicarbazide. This reaction is a standard method for forming semicarbazones and is relatively straightforward, making nitrofurazone accessible for production. The purity of the starting materials and controlled reaction conditions are crucial for achieving the high assay rates (often 98% or higher) that are required for its applications. For those seeking to buy nitrofurazone, ensuring the manufacturer adheres to strict synthesis protocols is paramount.

While nitrofurazone's historical use as a topical antibiotic is well-documented, its chemical stability and reactivity also lend themselves to its role as a research chemical and potential intermediate in the synthesis of other compounds. The nitro group and the furan ring are susceptible to various chemical transformations, offering avenues for further chemical modification and study. By thoroughly understanding the nitrofurazone chemical properties, researchers and manufacturers can best leverage this compound's potential.