NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier of specialized chemical compounds, including Flumazenil powder (CAS 78755-81-4). Understanding the chemical profile of this important pharmaceutical intermediate is key to appreciating its therapeutic applications and handling requirements.

Flumazenil, with the molecular formula C15H14FN3O3 and a molecular weight of 303.29, is known chemically as ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate. Its physical state is typically described as a white to off-white crystalline powder. The compound exhibits specific solubility characteristics, being soluble in DMSO, which is important for its formulation into injectable solutions, the primary route of clinical administration.

The melting point of Flumazenil is generally reported in the range of 201-203ºC, indicating its stability as a solid compound under ambient conditions. This stability, coupled with a high flash point of 273.1°C, contributes to its safety during storage and handling. The density and refractive index are also specified parameters for quality control, ensuring the consistency of the manufactured product.

As a pharmaceutical intermediate, Flumazenil powder's most critical application is its function as a benzodiazepine antagonist. This means it directly counteracts the sedative and hypnotic effects of benzodiazepines by binding to the same receptors in the brain. This makes it invaluable for reversing benzodiazepine overdose and for managing patients undergoing anesthesia who require a rapid return to consciousness. Its effectiveness as a benzodiazepine antagonist powder is well-documented in clinical practice.

The detailed chemical properties of Flumazenil powder, such as its PSA (4.43) and LogP (1.71), provide further insights into its behavior and interaction within biological systems. These parameters are important for pharmacokinetic and pharmacodynamic studies, as well as for optimizing drug delivery systems. The high purity, often exceeding 99%, supplied by NINGBO INNO PHARMCHEM CO.,LTD., is fundamental for its reliable use as a reverse sedation powder.

For researchers and pharmaceutical manufacturers, detailed chemical specifications are essential. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive information on its Flumazenil powder, ensuring that clients have access to the necessary data for their product development and quality assurance processes. The precise chemical profile of this compound underscores its vital role in enhancing patient safety and therapeutic outcomes in critical medical scenarios.