Understanding the precise chemical profile of an Active Pharmaceutical Ingredient (API) is fundamental for its successful application in drug manufacturing. Verapamil Hydrochloride, a vital cardiovascular agent, possesses specific physical and chemical characteristics that dictate its handling, storage, and therapeutic efficacy. This article provides an in-depth look at the chemical properties and specifications of Verapamil Hydrochloride, highlighting the importance of sourcing from reliable providers such as NINGBO INNO PHARMCHEM CO.,LTD.

Chemically, Verapamil Hydrochloride is known by its IUPAC name, which precisely describes its molecular structure. Its molecular formula is C27H39ClN2O4, and it has a molecular weight of approximately 491.06 g/mol. These parameters are critical for formulation calculations and ensuring the correct stoichiometry in synthesis processes.

In terms of physical appearance, Verapamil Hydrochloride is typically described as a white crystalline powder. It is odorless and has a bitter taste. The crystalline form is important for its solubility and stability. Manufacturers often specify requirements such as low loss on drying (typically ≤ 5%) and minimal sulphated ash (≤ 5%), which are indicators of purity and the absence of inorganic contaminants.

The purity of Verapamil Hydrochloride is a critical specification, often determined by High-Performance Liquid Chromatography (HPLC). Suppliers commonly guarantee a minimum purity of 98.0%, with many aiming for verapamil hydrochloride 99.0% purity or higher to meet the stringent demands of the pharmaceutical industry. For manufacturers looking to buy verapamil hydrochloride powder, verifying these purity levels through Certificates of Analysis (CoA) from trusted verapamil hydrochloride suppliers China like NINGBO INNO PHARMCHEM CO.,LTD. is essential.

Storage conditions are also crucial for maintaining the integrity of Verapamil Hydrochloride. It should be stored in a cool, dry, and well-closed container, protected from moisture and strong light or heat. Adherence to these conditions ensures its shelf life, which is typically two years when properly stored. This information is vital for inventory management and quality control throughout the supply chain.

Furthermore, adherence to pharmacopoeial standards such as BP2010, USP36, or CP2010 is a key specification. These standards define the acceptable limits for impurities, heavy metals (typically ≤ 10 PPM), and microbial counts (NMT 1000cfu/g), ensuring that the API is safe for pharmaceutical use. Access to verapamil hydrochloride bulk drug chemicals that meet these international standards is a significant advantage for manufacturers.

In conclusion, the detailed chemical profile of Verapamil Hydrochloride, encompassing its physical appearance, molecular structure, purity, and stability, is vital information for pharmaceutical manufacturers. By sourcing from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD., who provide comprehensive specifications and quality documentation, manufacturers can confidently procure this essential API, ensuring the quality and safety of their pharmaceutical products.