For chemists and product developers, a thorough understanding of a compound's chemical properties and synthesis pathways is fundamental to its effective utilization. 4-Methoxyacetophenone (CAS 100-06-1) is an aromatic ketone with a chemical formula of C9H10O2 and a molecular weight of 150.17 g/mol. Its structure features an acetophenone core with a methoxy group (-OCH3) substituted at the para-position of the benzene ring.

The compound is typically synthesized through the Friedel-Crafts acetylation of anisole. This classic organic reaction involves treating anisole with an acylating agent, such as acetyl chloride or acetic anhydride, in the presence of a Lewis acid catalyst like aluminum chloride. Modern advancements in synthesis may employ catalysts such as zeolites in continuous flow processes to improve efficiency and yield. The resulting product is a white to pale yellow crystalline solid with a melting point generally between 36-38°C.

Key chemical properties that contribute to its utility include its relative stability in alkaline media, making it suitable for applications like soap perfumes. It is soluble in organic solvents like ethanol and ether but only slightly soluble in water. The reactivity of the ketone group allows it to participate in various organic transformations, which is crucial for its role as an intermediate in synthesizing more complex molecules. At NINGBO INNO PHARMCHEM CO., LTD., we ensure that our 4-Methoxyacetophenone is produced with high purity and consistency, meeting the demanding specifications required for its diverse industrial applications. This attention to chemical integrity ensures reliable performance in all its uses.