At Ningbo Innopharmchem Co., Ltd., we are dedicated to providing essential chemical compounds that empower scientific research and industrial innovation. Among our key offerings is 7-Chloro-1-heptanol (CAS 55944-70-2), a compound renowned for its bifunctional nature and broad utility in organic synthesis and beyond. This colorless transparent liquid, characterized by a seven-carbon chain with a terminal hydroxyl group and a terminal chlorine atom, serves as a critical intermediate in numerous chemical transformations.

The physicochemical properties of 7-Chloro-1-heptanol are central to its application. With a molecular formula of C7H15ClO and a molecular weight of 150.64600, it exhibits a density of approximately 0.984 g/cm³. Its boiling point is around 213.6°C, and its flash point is 96.5°C, indicating moderate thermal stability that is well-suited for various reaction conditions. The presence of both a hydrophilic hydroxyl group and a hydrophobic chlorinated alkyl chain imparts an amphiphilic character, influencing its solubility and interfacial behavior. While it has limited solubility in water, it readily dissolves in common organic solvents, making it convenient for laboratory manipulations.

The true power of 7-Chloro-1-heptanol lies in its dual reactivity, making it an exceptionally versatile organic synthesis intermediate. The hydroxyl group can undergo oxidation to form aldehydes or carboxylic acids, esterification, or ether formation. Meanwhile, the terminal chlorine atom is an excellent leaving group, readily participating in nucleophilic substitution reactions (SN2). This allows for the introduction of a wide array of functionalities, such as amines, azides, or nitrils, at the seventh carbon position. This versatility enables chemists to construct complex molecular architectures with precision, a critical aspect in pharmaceutical development and specialty chemical synthesis.

In the pharmaceutical industry, 7-Chloro-1-heptanol serves as a crucial building block for synthesizing active pharmaceutical ingredients (APIs) and their intermediates. Its structure can be incorporated into drug candidates to modulate lipophilicity, reactivity, and overall pharmacokinetic profiles. Researchers utilize it to build complex molecular scaffolds, explore structure-activity relationships, and develop novel therapeutic agents targeting various diseases. The ability to precisely functionalize either end of the molecule provides a significant advantage in the intricate process of drug design.

Beyond pharmaceuticals, 7-Chloro-1-heptanol has significant applications in the specialty chemicals sector. Its amphiphilic nature makes it a valuable precursor for surfactants and emulsifiers, essential components in cosmetics, detergents, and industrial formulations. In material science, it can be used as a chain modifier in polymer synthesis, allowing for the introduction of specific end-group functionalities to create polymers with tailored properties for applications like coatings or advanced composites.

The synthesis of 7-Chloro-1-heptanol typically involves the chlorination of 1-heptanol using reagents like thionyl chloride or phosphorus trichloride, or the reduction of 7-chloroheptanoic acid. Rigorous quality control, including advanced analytical techniques like NMR and GC-MS, is employed by Ningbo Innopharmchem Co., Ltd. to ensure high purity (assay ≥98.0%) and minimal moisture content (≤0.2%), guaranteeing reliable performance in downstream applications.

For any chemical research or industrial application requiring a versatile bifunctional intermediate, 7-Chloro-1-heptanol is an excellent choice. We invite you to buy 7-chloro-1-heptanol from Ningbo Innopharmchem Co., Ltd. and experience the reliability and quality that drives scientific progress. Contact us for your supply needs and to learn more about how this compound can benefit your projects.