At NINGBO INNO PHARMCHEM CO.,LTD., we believe a deep understanding of chemical properties is the bedrock of successful scientific endeavors. Today, we focus on 2-Pipecoline, scientifically known as 2-Methylpiperidine (CAS: 109-05-7), a compound whose specific attributes make it invaluable in the realm of organic synthesis.

The core of 2-Pipecoline's utility lies in its molecular structure and resultant chemical behavior. As a derivative of piperidine, it possesses a nitrogen atom within a six-membered ring, which confers basicity and nucleophilic properties. These traits are essential for its role as a reagent in various chemical reactions, including alkylations and as a building block in the synthesis of heterocyclic compounds. The presence of the methyl group at the second position subtly influences its reactivity and steric profile, differentiating it from unsubstituted piperidine.

Examining the physical properties of 2-Methylpiperidine further illuminates its practical applications. It is typically described as a clear yellow liquid with a relatively low melting point (-4 to -5°C) and a boiling point around 118-119°C. This liquid state at room temperature, combined with its solubility in water and common organic solvents, facilitates its handling and integration into various reaction systems. Furthermore, its specific gravity (density) of 0.844 g/mL is a key parameter for volumetric measurements in synthesis. Understanding these 2-methylpiperidine properties allows chemists to optimize reaction conditions and ensure efficient process design.

The low water content, often specified as less than or equal to 0.25%, is another critical characteristic, especially for reactions sensitive to moisture. This detail, along with its flash point (around 47°F or 16°C), underscores the need for proper storage and handling, as detailed in our discussions on 2-methylpiperidine safety and handling. By appreciating the detailed chemical and physical profile of 2-Pipecoline, professionals can better leverage its potential in driving chemical innovation.