The landscape of modern chemical synthesis is continually evolving, driven by the demand for complex molecules with precise structures and functions. Within this dynamic field, protected amino acids are indispensable tools, and Boc-D-His(Bom)-OH stands out for its strategic utility. This article examines the chemical versatility of Boc-D-His(Bom)-OH, highlighting its role as a critical synthesis reagent and its importance in custom peptide synthesis and broader organic chemistry applications.

Boc-D-His(Bom)-OH, identified by its CAS number 99310-01-7, is a derivative of D-histidine that incorporates two key protecting groups: tert-butyloxycarbonyl (Boc) and benzyloxymethyl (Bom). The Boc group typically safeguards the alpha-amino function, readily removable under acidic conditions. Concurrently, the Bom group provides protection to the imidazole ring of histidine, a reactive site that can interfere with peptide coupling if not adequately shielded. This dual protection strategy offers orthogonal deprotection capabilities, allowing for sequential manipulation of the amino acid during the assembly of peptide chains. This makes it an invaluable component for researchers looking to buy Boc-D-His(Bom)-OH online for their specialized projects.

The chemical properties of Boc-D-His(Bom)-OH, including its molecular formula (C19H25N3O5) and molecular weight (375.42 g/mol), are well-defined, ensuring predictability in synthetic reactions. Its typical form as a white powder, along with physical constants like density (1.21 g/cm³), boiling point (595.3°C), and flash point (313.8°C), are critical data points for chemists and process engineers. As a synthesis reagent, its purity and consistent physical form directly influence the success rate and efficiency of intricate chemical synthesis pathways.

The demand for this specific amino acid derivative is closely tied to the advancements in peptide-based therapeutics and the growing field of custom peptide synthesis. The ability to precisely incorporate histidine residues with controlled side-chain protection is essential for creating peptides with specific biological activities or structural characteristics. Therefore, identifying reliable N-tert-Butyloxycarbonyl-N'-benzyloxymethyl-D-histidine suppliers is a crucial step for research laboratories and pharmaceutical companies. These suppliers not only provide the material but also ensure that the chemical meets the rigorous standards required for pharmaceutical development.

The Boc-D-His(Bom)-OH price can vary based on factors such as scale, purity, and supplier. However, its versatility as a building block in organic chemistry extends beyond just peptide synthesis. It can be used in the synthesis of complex heterocyclic compounds or as a chiral auxiliary in asymmetric synthesis. For those needing to procure this compound, understanding the market and finding a dependable N-tert-Butyloxycarbonyl-N'-benzyloxymethyl-D-histidine supplier that offers competitive Boc-D-His(Bom)-OH CAS 99310-01-7 pricing is key to advancing their research and development efforts effectively.