Exploring the Synthesis and Chemical Characteristics of 2-Ethyl-4-methylimidazole
2-Ethyl-4-methylimidazole (EMI-24) is a chemical compound of significant industrial importance, primarily recognized for its utility as an organic synthesis intermediate and an epoxy resin curing agent. Understanding its synthesis and intrinsic chemical properties is key to appreciating its applications and ensuring its effective use in manufacturing. This exploration delves into the typical synthetic routes for EMI-24 and highlights its defining chemical characteristics.
The synthesis of 2-Ethyl-4-methylimidazole typically involves reactions that build the imidazole ring structure with the desired ethyl and methyl substituents. One common approach involves the condensation of precursors such as 2-aminopropanal derivatives with nitriles under specific catalytic conditions. For example, reacting a suitable propanal derivative with propanonitrile in the presence of a catalyst like cuprous bromide, followed by appropriate work-up and purification steps, can yield EMI-24. Another synthetic strategy might involve multi-component reactions or cyclization processes tailored to form the substituted imidazole ring efficiently. The focus for manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is on optimizing these synthesis of 2-ethyl-4-methylimidazole processes to achieve high yields, purity, and cost-effectiveness.
The chemical properties of 2-Ethyl-4-methylimidazole are central to its functionality. Physically, it is often described as a light yellow powder or a yellowish viscous liquid, depending on the specific grade and ambient temperature. Its melting point is typically in the range of 47-54°C, and it has a relatively high boiling point, around 293.5°C at standard atmospheric pressure. This suggests it is not highly volatile under normal conditions, contributing to its easier handling and storage. The compound's exact mass is recorded as 110.084396, and its molecular formula is C6H10N2, with a molecular weight of approximately 110.16 g/mol.
The polarity and solubility of EMI-24 are also significant. With a polar surface area (PSA) of 28.68000 and a LogP value of 0.62, it exhibits a balanced lipophilic-hydrophilic nature, which aids its reactivity in various organic media. It is noted to be soluble in water and many organic solvents. Its flash point is around 136.8 ± 5.1 °C, indicating a moderate flammability risk that requires standard precautions during handling and storage.
The value proposition of 2-Ethyl-4-methylimidazole lies in these precise chemical properties of EMI-24. As an organic synthesis intermediate, these properties dictate its suitability for specific reactions and its ability to integrate into complex molecular structures. Furthermore, its function as an epoxy curing agent is directly linked to its catalytic activity, influenced by the electronic and steric nature of the imidazole ring and its substituents. Businesses looking to source high-quality EMI-24 for their manufacturing needs often consult detailed specifications and reliability reports from suppliers of 2-Ethyl-4-methylimidazole, such as NINGBO INNO PHARMCHEM CO.,LTD., who ensure adherence to stringent quality controls.
The ability to buy 2-Ethyl-4-methylimidazole from reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that these critical chemical properties are maintained, allowing for consistent performance in end applications. Whether used in the synthesis of novel pharmaceuticals, advanced agrochemicals, or high-performance epoxy resins, a thorough understanding of EMI-24's synthesis and chemical characteristics is fundamental to unlocking its full potential.
Perspectives & Insights
Data Seeker X
“62, it exhibits a balanced lipophilic-hydrophilic nature, which aids its reactivity in various organic media.”
Chem Reader AI
“1 °C, indicating a moderate flammability risk that requires standard precautions during handling and storage.”
Agile Vision 2025
“The value proposition of 2-Ethyl-4-methylimidazole lies in these precise chemical properties of EMI-24.”