Understanding the synthesis and reactivity of key chemical intermediates is fundamental to their effective application. Ningbo Inno Pharmchem Co., Ltd. focuses on providing compounds like (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate, along with insights into their chemical behavior, to support research and development across industries.

The synthesis of (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate typically involves several strategic steps to assemble its distinct functional components. While specific proprietary methods vary, general approaches often begin with readily available chiral precursors. Key transformations include the introduction of the cyano group, often via nucleophilic substitution using cyanide salts, and the installation of the tert-butyl carbamate protecting group on an amine functionality. The iodophenyl moiety is usually incorporated through electrophilic aromatic substitution or by coupling reactions involving an iodinated aromatic starting material. The precise control over stereochemistry is maintained throughout these processes to ensure the final product's enantiomeric purity. Reliable (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate chemical synthesis by specialized manufacturers is crucial.

The reactivity of (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate is dictated by its functional groups. The aryl iodide is a prime candidate for a broad spectrum of palladium-catalyzed cross-coupling reactions. These include Suzuki-Miyaura coupling with boronic acids, Sonogashira coupling with terminal alkynes, and Heck reactions with alkenes, allowing for the efficient formation of C-C bonds. This reactivity is essential for building complex molecular scaffolds. Similarly, the cyano group offers a gateway to various transformations: it can be reduced to a primary amine (R-CH2NH2) using reagents like LiAlH4 or catalytic hydrogenation, or hydrolyzed to a carboxylic acid (R-COOH) under acidic or basic conditions. The tert-butyl carbamate (Boc) protecting group on the amine can be readily removed under mild acidic conditions (e.g., TFA), liberating the free amine for subsequent derivatization, such as acylation or alkylation.

Researchers seeking to utilize this intermediate can rely on its specific identification through its CAS number, 1159489-37-8. Sourcing from a reputable (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate supplier ensures that the material meets stringent purity and quality standards necessary for these reactions.

Ningbo Inno Pharmchem Co., Ltd. is committed to providing high-quality chemical intermediates that facilitate groundbreaking research. Our expertise in the synthesis and handling of compounds like (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate ensures that our clients have access to reliable materials for their synthetic endeavors. We aim to be a cornerstone for innovation by offering well-characterized products and supporting the advancement of chemical science.

In conclusion, understanding the synthesis pathways and the diverse reactivity of (S)-tert-butyl (1-cyano-2-(4-iodophenyl)ethyl)carbamate unlocks its full potential as a building block in modern chemistry. Ningbo Inno Pharmchem Co., Ltd. is dedicated to supplying this valuable compound to the scientific community.