Ethyl 6-Methyl-5-nitronicotinate, identified by its CAS number 1211538-09-8, is a compound that plays a significant role in the chemical industry, particularly as an intermediate in organic synthesis and pharmaceutical manufacturing. Its structure, a pyridine derivative with specific functional groups, lends itself to a variety of chemical transformations, making it a valuable building block. NINGBO INNO PHARMCHEM CO.,LTD. is a key provider of this essential chemical, facilitating research and industrial processes.

The synthesis of Ethyl 6-Methyl-5-nitronicotinate typically involves the careful introduction of a nitro group onto a pyridine ring, alongside esterification and methylation. While specific proprietary methods exist, common routes often involve the nitration of a precursor like ethyl 6-methylnicotinate or related derivatives. This nitration step is crucial and requires precise control over reaction conditions, such as temperature, concentration of nitrating agents (like nitric acid and sulfuric acid), and reaction time, to ensure regioselectivity and minimize unwanted side products. The successful synthesis is vital for researchers looking to buy ethyl 6-methyl-5-nitronicotinate for their projects.

The compound's physical properties include being a solid, often white to light yellow crystalline powder, although it can also appear as a liquid depending on purity and ambient conditions. Its molecular formula is C9H10N2O4, with a molecular weight of 210.19. These fundamental chemical characteristics are important for handling, storage, and subsequent reactions. Proper storage, typically under an inert atmosphere at room temperature, is recommended to maintain its chemical integrity. This attention to detail is something NINGBO INNO PHARMCHEM CO.,LTD. emphasizes in its product handling.

In terms of applications, Ethyl 6-Methyl-5-nitronicotinate is highly sought after as an intermediate in the pharmaceutical industry. It serves as a precursor for synthesizing more complex drug molecules, including those targeting various diseases. The pyridine ring system is a common pharmacophore, and the nitro group can be converted into an amino group, which is a versatile handle for further modifications like acylation or alkylation, allowing for the creation of diverse chemical libraries for drug screening. This makes it an indispensable tool for medicinal chemists.

Beyond pharmaceuticals, it also finds utility in general organic synthesis for creating novel compounds with specific functionalities. Its reactivity allows it to participate in a range of reactions, including nucleophilic substitutions and reductions. The presence of the nitro group can activate the ring for certain reactions, and its conversion to an amine opens up entirely new synthetic avenues. The continued demand for organic synthesis intermediates like this highlights its importance in chemical innovation.

For academic institutions and industrial laboratories, sourcing reliable chemical intermediates is paramount. Working with established suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to compounds that meet rigorous quality standards. Understanding the chemical properties and synthesis of Ethyl 6-Methyl-5-nitronicotinate allows researchers to better plan their synthetic strategies and anticipate reaction outcomes. Whether it's for creating new therapeutic agents or exploring novel chemical structures, this compound remains a fundamental building block in the modern chemical landscape, a testament to the ongoing demand for high-quality pharmaceutical intermediate chemicals.