At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing essential building blocks for scientific advancement. One such critical compound is N-(4-sulfamoylphenyl)acrylamide, also known as N-[4-(aminosulphonyl)phenyl]acrylamide, with the CAS number 2621-99-0. This chemical compound, often abbreviated as ASPAA, is a versatile molecule with significant utility in both the pharmaceutical sector and advanced material sciences. Understanding its synthesis and properties is key to leveraging its full potential.

The synthesis of N-(4-sulfamoylphenyl)acrylamide typically involves reactions with readily available starting materials. A common method includes the reaction of sulfanilamide with acrylyl chloride in the presence of a base like pyridine, often carried out in a solvent such as 1,4-dioxane. This process yields the desired product with high purity, making it suitable for demanding applications. The resulting white crystalline powder possesses a melting point of around 215°C, indicating its stable nature.

The applications of ASPAA are diverse and impactful. As a pharmaceutical intermediate, it is instrumental in the creation of macromolecular drugs. These drugs are designed to be water-soluble, possess low toxicity, and offer sustained-release effects. This is particularly important for chronic conditions where consistent drug levels are crucial. The development of such advanced drug delivery systems is a major area of pharmaceutical research, and ASPAA provides a key monomer for achieving these goals. By incorporating ASPAA into polymer chains, NINGBO INNO PHARMCHEM CO.,LTD. supports the creation of next-generation therapeutics.

In the field of material science, N-[4-(aminosulphonyl)phenyl]acrylamide is also recognized for its role in producing high-performance lithographic printing plates. When copolymerized with other monomers, such as acrylates, ASPAA enhances the properties of these plates. The presence of the sulfonamide group imbues the resulting polymers with a certain alkali solubility, which is critical for the development process of printing plates. This leads to improved alkali development characteristics, wider development latitude, and greater printing resistance. These qualities are essential for achieving precise, durable prints in various graphic arts applications.

The dual utility of ASPAA as both a pharmaceutical intermediate and a material science component underscores its importance in the chemical supply chain. NINGBO INNO PHARMCHEM CO.,LTD. is committed to ensuring a reliable supply of this high-quality compound to support innovation in these fields. If you are looking to purchase N-[4-(aminosulphonyl)phenyl]acrylamide for your research or production needs, consider NINGBO INNO PHARMCHEM CO.,LTD. as your trusted partner.