Azelaic acid, scientifically termed Nonanedioic acid and identified by CAS number 123-99-9, is a saturated linear dicarboxylic acid with the chemical formula (CH2)7(CO2H)2. Its molecular structure, featuring two carboxyl groups separated by a seven-carbon chain, dictates its diverse chemical behavior and broad industrial applicability. At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing this essential chemical, highlighting its fundamental properties and significance.

As a white crystalline powder, azelaic acid exhibits a moderate melting point, facilitating its handling in various industrial processes. Its solubility profile is characteristic of medium-chain dicarboxylic acids: it is slightly soluble in water but readily dissolves in polar organic solvents such as ether and ethanol. This solubility makes it amenable to a wide range of chemical reactions and formulations, whether for pharmaceutical preparations or industrial syntheses. The ability to readily form esters is particularly noteworthy, as these derivatives are crucial for lubricants and plasticizers.

The reactivity of the carboxyl groups on azelaic acid allows it to participate in esterification, amidation, and polymerization reactions. For instance, its reaction with diamines leads to the formation of polyamides, including Nylon-6,9, a specialized polymer known for its desirable mechanical and thermal properties. In the production of lubricants and plasticizers, esterification with various alcohols yields compounds with specific viscosity, thermal stability, and flexibility characteristics, essential for high-performance applications. Understanding the chemical reactions of azelaic acid is key to harnessing its potential in material science.

Beyond its industrial utility, the chemical properties of azelaic acid are also responsible for its therapeutic effects. Its anti-inflammatory and antimicrobial actions, particularly against Propionibacterium acnes, are well-established. These biological activities are linked to its chemical structure and its ability to interact with cellular processes. The production of pharmaceutical grade azelaic acid requires rigorous control over chemical synthesis and purification to ensure the absence of unwanted byproducts and impurities, guaranteeing safety and efficacy for medical use.

In essence, the chemistry of azelaic acid is central to its value across multiple sectors. From its role as a precursor in polymer synthesis and lubricant formulation to its therapeutic applications in dermatology, its chemical properties underpin its industrial significance. NINGBO INNO PHARMCHEM CO.,LTD. provides access to this vital chemical, enabling innovation and production across diverse industries.