Navigating the landscape of industrial chemicals requires a thorough understanding of their characteristics, production methods, and safety guidelines. 3-Chloroaniline (CAS 108-42-9) is a prime example of a chemical intermediate with significant industrial utility, but also one that demands careful handling due to its inherent properties. This article aims to provide a detailed overview of 3-Chloroaniline, focusing on its properties, production, and the critical safety measures required for its use in industrial settings.

3-Chloroaniline, also known by synonyms such as m-Chloroaniline or 3-Chlorobenzenamine, presents as a clear pale yellow to brown liquid. Its physical state and color can vary slightly, sometimes darkening upon prolonged exposure to air or light, a common trait for aniline derivatives. With a molecular weight of 127.57 and a CAS number of 108-42-9, it is moderately soluble in water but readily dissolves in common organic solvents like ethanol and ether. These physicochemical properties are crucial for its application in various reaction systems.

The production of 3-Chloroaniline primarily involves the reduction of 3-chloronitrobenzene. This process is typically carried out through hydrogenation, often utilizing noble metal catalysts or noble metal sulfides. The addition of metal oxides during the reaction is a key technique employed to prevent dehalogenation, ensuring a high yield of the desired product, often around 98%. This controlled synthesis process is vital for achieving the high purity levels, typically 99.5% minimum, that are necessary for its downstream applications.

The applications of 3-Chloroaniline are diverse, spanning the synthesis of dyes, pharmaceuticals, and agrochemicals. In the dye industry, it's a vital component for azo dyes. For pharmaceuticals, it serves as an intermediate for diuretic and antihypertensive drugs, among others. In agriculture, it's used in the production of herbicides and pesticides. The consistent demand for these products means that securing a reliable supply of 3-Chloroaniline from reputable 3-Chloroaniline suppliers is a strategic priority for many companies.

Safety is a paramount concern when handling 3-Chloroaniline. The chemical is classified as toxic, with hazards associated with inhalation, skin contact, and ingestion. It can cause methaemoglobinemia, leading to cyanosis, and potential long-term effects. Therefore, stringent safety protocols must be observed. This includes working in well-ventilated areas, using appropriate personal protective equipment (PPE) such as gloves, eye protection, and respiratory protection, and adhering to proper storage and disposal procedures. The chemical's classification and handling requirements underscore the importance of consulting detailed Safety Data Sheets (SDS) before use.

For industries looking to leverage the capabilities of 3-Chloroaniline, understanding the 3-Chloroaniline price and sourcing from dependable 3-Chloroaniline suppliers are key considerations. The competitive market, especially in regions like China, offers various options for procurement. Ensuring that suppliers adhere to quality and safety standards is as crucial as obtaining a favorable 3-Chloroaniline price.

In summary, 3-Chloroaniline is a fundamental chemical intermediate whose utility is matched by the necessity for diligent handling. By understanding its properties, production pathways, and implementing robust safety measures, industrial users can effectively and safely harness its potential in developing innovative products for a variety of sectors.