NINGBO INNO PHARMCHEM CO.,LTD. provides Methyl Chloroglyoxylate (CAS 5781-53-3), a compound of significant interest due to its unique chemical properties and applications. Understanding these characteristics is crucial for its effective use and safe handling in research and industrial environments. Methyl chloroglyoxylate is a highly reactive organic molecule, classified as a potent acylating agent, making it a valuable building block in numerous synthetic pathways.

Chemically, methyl chloroglyoxylate possesses a molecular formula of C3H3ClO3 and a molecular weight of approximately 122.51 g/mol. It typically appears as a clear, light yellow liquid with a pungent odor. Its high reactivity stems from the presence of both a carbonyl chloride group and an ester group within its structure. This dual functionality allows it to readily participate in reactions such as acylation, cyclization, and nucleophilic substitutions. Its notable reactivity also means it is sensitive to moisture, reacting vigorously with water to release hydrochloric acid fumes and other byproducts.

The primary uses of methyl chloroglyoxylate revolve around its application as a synthetic reagent. It is instrumental in the preparation of fused coumarins, substituted isoxazoles, and various other heterocycles, which are foundational structures in pharmaceuticals and agrochemicals. Its role in creating complex molecular architectures and its utility in enantioselective synthesis further underscore its importance in advanced chemical research.

Given its hazardous nature, adhering to methyl chloroglyoxylate safety data is paramount. The compound is classified as flammable, corrosive, and harmful if swallowed or inhaled. It can cause severe skin burns and eye damage. Therefore, when handling methyl chloroglyoxylate, it is imperative to wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and a respirator if working in an area with insufficient ventilation. Work should always be conducted in a well-ventilated fume hood.

Proper storage is also critical. Methyl chloroglyoxylate should be stored in a cool, dry place, away from incompatible materials such as water, strong bases, alcohols, and oxidizing agents. Its hygroscopic nature necessitates storage in tightly sealed containers to prevent degradation and hazardous reactions. Ensuring a reliable supply of this chemical, often through purchasing from reputable methyl chloroglyoxylate suppliers, is vital for uninterrupted research and production.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality methyl chloroglyoxylate and comprehensive safety information to our clients. Understanding the methyl chloroglyoxylate chemical properties and following strict safety protocols are essential for maximizing its benefits while minimizing risks in any laboratory or industrial setting.