Ningbo Inno Pharmchem Co., Ltd. specializes in providing high-quality fine chemicals, and today we focus on the essential aspects of 3,5-Dimethyl-4-iodophenol (CAS 80826-86-4), particularly its chemical properties and the best practices for its handling and storage.

3,5-Dimethyl-4-iodophenol is a compound that commands attention in the realm of organic synthesis due to its specific molecular structure and reactivity. Physically, it is described as a white to off-white crystalline powder. This appearance is a key indicator of its purity and consistency. A significant physical characteristic is its melting point, which has been reliably recorded at 129°C. This melting point is not merely a data point; it serves as a critical parameter for quality control during manufacturing and for users in determining suitable reaction conditions or storage temperatures.

Chemically, 3,5-Dimethyl-4-iodophenol, with the molecular formula C8H9IO, possesses a benzene ring substituted with two methyl groups, a hydroxyl group, and an iodine atom. This combination of functional groups imparts distinct chemical behavior. The iodine atom makes it susceptible to various substitution and coupling reactions, such as Suzuki, Heck, and Sonogashira couplings, which are fundamental in constructing more complex organic molecules. The phenolic hydroxyl group can undergo reactions like etherification, esterification, or serve as a directing group in electrophilic aromatic substitution reactions. These inherent chemical properties make it a versatile intermediate for synthesizing a wide array of valuable compounds, including active ingredients for pharmaceuticals and agrochemicals.

While incredibly useful, understanding the safety aspects of 3,5-Dimethyl-4-iodophenol is paramount. Information from various sources, including Safety Data Sheets (SDS), indicates that this compound can be an irritant. Specifically, it may cause irritation to the eyes, respiratory system, and skin. Therefore, when handling this chemical, it is crucial to adhere to strict laboratory safety protocols. This includes wearing appropriate personal protective equipment (PPE) such as safety goggles, chemical-resistant gloves, and protective clothing. Ensuring adequate ventilation in the workspace is also essential to minimize inhalation exposure.

Proper storage is another critical factor in maintaining the integrity and safety of 3,5-Dimethyl-4-iodophenol. The compound is noted to be light-sensitive. Prolonged exposure to light can degrade the chemical, affecting its purity and reactivity. Consequently, it should be stored in tightly sealed containers, preferably made of amber glass or other light-blocking materials, in a cool, dry, and well-ventilated area. Some recommendations also suggest storage under an inert atmosphere, such as nitrogen or argon, especially for long-term preservation. Adhering to these storage guidelines ensures that the chemical remains stable and effective for its intended applications.

Ningbo Inno Pharmchem Co., Ltd. is committed to providing comprehensive information and high-quality products to our clients. We understand that detailed knowledge of chemical properties and safe handling practices is as important as the product itself. By offering reliable 3,5-Dimethyl-4-iodophenol (CAS 80826-86-4) and providing this essential technical guidance, we aim to support the success and safety of your chemical synthesis endeavors.