N-(2-Hydroxyethyl)phthalimide, identified by CAS 3891-07-4, is a compound of significant interest in organic chemistry due to its specific chemical structure and resultant reactivity. The presence of the phthalimide group, a cyclic imide, and the attached hydroxyethyl chain imparts unique characteristics that make it a valuable synthetic intermediate. Understanding these properties is key to effectively utilizing this compound in various chemical transformations.

The compound typically presents as a White Crystalline Powder, with a melting point generally ranging from 126°C to 135°C. This solid form at room temperature simplifies handling and storage. The refractive index is estimated around 1.622, a parameter useful for identification and quality control. Chemically, the N-H bond within the phthalimide structure is acidic, though less so than in simpler imides. More importantly, the terminal hydroxyl group (-OH) on the ethyl chain is a primary alcohol, which is highly reactive. This hydroxyl group can undergo a wide array of reactions, including esterification, etherification, oxidation, and nucleophilic substitution after activation (e.g., conversion to a halide or tosylate).

The phthalimide moiety itself is known for its utility in protecting primary amines, as famously demonstrated in the Gabriel synthesis. While N-(2-Hydroxyethyl)phthalimide is not directly involved in the classic Gabriel synthesis for primary amines, the phthalimide group influences the molecule's electronic properties and stability. It can also participate in certain ring-opening reactions under specific conditions. The interplay between the phthalimide and the hydroxyethyl functional groups allows for sequential or concerted reactions, offering versatile pathways for synthesizing complex organic molecules.

NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of understanding these chemical properties when researchers select N-(2-Hydroxyethyl)phthalimide for their projects. The compound's reactivity profile makes it an excellent candidate for building more elaborate structures, whether for pharmaceutical intermediates, specialized organic compounds, or potentially in the development of novel materials. By providing high-purity N-(2-Hydroxyethyl)phthalimide, NINGBO INNO PHARMCHEM CO.,LTD. supports scientists in unlocking the full potential of this versatile chemical intermediate.