A deep understanding of a chemical compound's properties is the bedrock of its successful application in scientific research and industrial processes. 2,4,6-Trifluoroaniline, a key fine chemical intermediate with CAS number 363-81-5, possesses a unique set of characteristics that dictate its utility in synthesis and material science. This article aims to elucidate these properties, providing valuable insights for chemists and manufacturers.

At its core, 2,4,6-Trifluoroaniline is an aromatic amine characterized by the presence of three fluorine atoms strategically positioned on the benzene ring. This fluorination pattern significantly influences its electronic density distribution and reactivity. The fluorine atoms are highly electronegative, withdrawing electron density from the ring and affecting the basicity of the amino group. This makes the amino group less nucleophilic compared to aniline itself, a trait that chemists leverage in specific synthetic pathways.

Physically, 2,4,6-Trifluoroaniline typically presents as a white crystalline solid. Its melting point is a critical parameter for identification and purity assessment, generally falling within the range of 33-37°C. This relatively low melting point means it can be easily handled and processed in various laboratory and industrial settings. Its boiling point is recorded at approximately 57°C at 22 mmHg, indicating its volatility under reduced pressure.

Solubility is another crucial property. 2,4,6-Trifluoroaniline is noted to be insoluble in water, a characteristic common to many fluorinated organic compounds due to their hydrophobic nature. However, it is generally soluble in common organic solvents such as ethanol, methanol, ether, and chloroform. This solubility profile is vital for selecting appropriate reaction media and purification methods. For example, when looking to buy 2,4,6-Trifluoroaniline CAS 363-81-5, understanding its solubility helps in planning experimental setups.

The molecular formula of 2,4,6-Trifluoroaniline is C6H4F3N, with a molecular weight of approximately 147.10 g/mol. Its chemical structure, with the CAS number 363-81-5, makes it a versatile building block. It readily participates in reactions typical of aromatic amines, such as diazotization, acylation, and alkylation, but with modifications due to the electron-withdrawing effect of the fluorine atoms. The specific 2,4,6-Trifluoroaniline synthesis routes often exploit these modified reactivities.

For manufacturers and researchers, having access to reliable suppliers of high-purity 2,4,6-Trifluoroaniline is essential. Companies like NINGBO INNO PHARMCHEM CO.,LTD. provide this compound with detailed specifications, enabling users to confirm its properties align with their needs. By understanding the intricate properties of 2,4,6-Trifluoroaniline, one can better appreciate its utility in areas like the uses of 2,4,6-trifluorobenzenamine in pharmaceutical intermediates and advanced material synthesis.

In conclusion, the detailed chemical and physical properties of 2,4,6-Trifluoroaniline are fundamental to its successful application. Its solid form, specific melting and boiling points, and solubility characteristics, combined with its unique electronic structure, position it as an indispensable intermediate for modern chemical synthesis and material development.