Understanding the Properties and Handling of 3-Iodoanisole
For chemists and material scientists, a thorough understanding of a compound's properties is fundamental to its successful application. 3-Iodoanisole (CAS: 766-85-8) is a fine chemical intermediate with specific characteristics that dictate its use and handling, particularly in sensitive synthesis processes.
Physically, 3-Iodoanisole is typically described as a liquid. Its appearance can range from clear yellow to pink-brown or red, often depending on its purity and age. The compound has a relatively high density, around 1.7 to 1.9 g/cm³, and a boiling point of approximately 244-245 °C at standard pressure. Its flash point is also notable, typically above 100 °C, indicating a degree of flammability that requires appropriate safety measures. When sourcing from providers like NINGBO INNO PHARMCHEM CO.,LTD., specifications on these properties are readily available, ensuring users can anticipate its behavior in various reactions.
Chemically, the presence of the iodine atom makes 3-Iodoanisole a reactive aryl halide. This reactivity is central to its utility as a synthetic intermediate. However, it is also noted for its sensitivity to light. Prolonged exposure to light can lead to decomposition, potentially affecting its purity and efficacy. Therefore, proper storage conditions are crucial. It should be kept in tightly sealed containers, protected from light, and stored in a cool, well-ventilated area. These precautions are vital for maintaining the compound's quality, especially when one needs to buy 3-iodoanisole for critical research or manufacturing.
Solubility is another key property. 3-Iodoanisole is generally soluble in common organic solvents such as ethanol, ether, and chloroform. This solubility profile makes it compatible with a wide range of reaction media commonly used in organic synthesis. Conversely, it exhibits limited solubility in water due to its hydrophobic nature. This differential solubility can be leveraged in extraction and purification processes.
When handling 3-Iodoanisole, standard laboratory safety practices should be followed. Due to its potential irritant properties (H319 - causes serious eye irritation, H335 - may cause respiratory irritation), appropriate personal protective equipment (PPE) such as gloves, eye protection, and lab coats should be worn. In case of contact, flushing with water is recommended. For inhalation, moving to fresh air is advised. Accessing the Safety Data Sheet (SDS) from the supplier is always the best practice for detailed safety information.
In conclusion, understanding the physical and chemical properties of 3-Iodoanisole, alongside its light sensitivity, is paramount for its effective and safe use. By adhering to proper handling and storage guidelines, researchers and manufacturers can maximize its potential as a critical intermediate in the fine chemical industry, often sourced from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
Perspectives & Insights
Data Seeker X
“Its flash point is also notable, typically above 100 °C, indicating a degree of flammability that requires appropriate safety measures.”
Chem Reader AI
“, specifications on these properties are readily available, ensuring users can anticipate its behavior in various reactions.”
Agile Vision 2025
“Chemically, the presence of the iodine atom makes 3-Iodoanisole a reactive aryl halide.”