Valerophenone, a prominent aromatic ketone with the CAS number 1009-14-9, is a compound that plays a significant role in both academic research and industrial chemical synthesis. Its molecular structure, characterized by a phenyl group attached to a valeroyl moiety, grants it a unique set of chemical properties that are exploited in various applications. Understanding these properties is key to appreciating its value as a versatile chemical intermediate.

Chemically, Valerophenone is a colorless liquid with a molecular formula of C11H14O and a molecular weight of approximately 162.23 g/mol. Its physical state as a liquid at room temperature, combined with its reactivity centered around the carbonyl group, makes it amenable to a wide range of chemical transformations. The presence of the phenyl ring imparts aromatic character, influencing its electronic properties and reactivity in electrophilic substitution reactions. As a ketone, it readily undergoes nucleophilic addition reactions and can participate in condensation reactions, making it a valuable synthon.

The primary utility of Valerophenone lies in its extensive applications within organic synthesis. It serves as a crucial starting material and intermediate for the creation of more complex molecules. Its involvement in Friedel-Crafts acylation, as previously noted, allows for the efficient introduction of the pentanoyl group onto aromatic systems. This is a foundational step in the synthesis of many pharmaceuticals, fragrances, and specialty chemicals. Furthermore, Valerophenone can be utilized in reductive amination, Wittig reactions, and various other transformations that build carbon skeletons or introduce functional groups, underscoring its versatility in constructing molecular diversity.

In research settings, Valerophenone is also recognized for its photochemical properties and its activity as an inhibitor of carbonyl reductase. These biological and physical characteristics broaden its scope of application beyond traditional synthesis, making it a multidisciplinary research chemical. For laboratories requiring this compound, sourcing it from reliable chemical suppliers ensures the necessary purity and consistent quality for demanding experimental protocols. The accessibility of Valerophenone through various distributors means that researchers worldwide can readily obtain this important compound for their work.