NINGBO INNO PHARMCHEM CO.,LTD. is a premier supplier of specialized chemical intermediates, including the versatile Fmoc-D-2-Nitrophenylalanine. Understanding its chemical properties is key to leveraging its full potential in various synthesis applications.

Fmoc-D-2-Nitrophenylalanine (CAS 478183-70-9) is characterized by its Fmoc (fluorenylmethyloxycarbonyl) protecting group and a phenylalanine backbone featuring a nitro group at the ortho position of the phenyl ring. This unique combination imparts specific chemical reactivity and stability. The Fmoc group is renowned for its base-lability, allowing for selective deprotection under mild basic conditions, such as with piperidine, without affecting other sensitive functional groups. This feature is critical for controlled chain elongation in peptide synthesis. Researchers frequently seek to buy Fmoc-D-2-Nitrophenylalanine for its predictable behavior and compatibility with standard Fmoc/tBu SPPS protocols.

The presence of the nitro group significantly influences the electronic nature of the phenyl ring. This electron-withdrawing group can alter the reactivity of adjacent positions and can itself serve as a functional handle for further chemical transformations, such as reduction to an amino group. This opens up possibilities for creating more complex derivatives or for use in specific coupling reactions. The price of Fmoc-D-2-Nitrophenylalanine is often considered in the context of its utility as a sophisticated building block for challenging synthetic targets. NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers have access to this compound with the necessary purity for demanding applications.

The applications of this compound extend beyond traditional peptide synthesis. As a key component among unnatural amino acids in drug discovery, it allows for the rational design of peptides with modified pharmacological properties. The peptide synthesis building blocks provided by NINGBO INNO PHARMCHEM CO.,LTD., including Fmoc-D-2-Nitrophenylalanine, are crucial for advancing research in areas like medicinal chemistry and the development of novel biomaterials. The rigorous quality control applied to these products ensures their suitability for complex synthetic routes, making them indispensable for scientists worldwide.

The chemical properties of Fmoc-D-2-Nitrophenylalanine make it an invaluable intermediate for a wide array of advanced chemical synthesis projects.