At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing comprehensive information about the chemical compounds we supply, enabling our clients to make informed decisions for their research and development needs. N-[2-(Boc-amino)ethyl]glycine ethyl ester, identified by CAS number 72648-80-7, is a key intermediate with valuable chemical properties and well-established synthesis pathways, making it essential for peptide synthesis and broader organic synthesis applications.

The chemical structure of N-[2-(Boc-amino)ethyl]glycine ethyl ester is central to its functionality. It features a Boc (tert-butyloxycarbonyl) protecting group attached to one of the nitrogen atoms, which shields this amine from unwanted reactions during synthesis. This protection is crucial as it allows for selective reactions to occur at other sites of a molecule. The presence of an ethyl ester group at the other end provides a reactive site for nucleophilic attack, ester hydrolysis, or transesterification, further enhancing its versatility as a chemical building block. Typically described as a colorless to yellow liquid or a pale yellow to white solid, its appearance can vary slightly depending on purity and storage conditions. High purity, often exceeding 98% by GC, is generally required for its use as a reliable reagent.

The synthesis of N-[2-(Boc-amino)ethyl]glycine ethyl ester commonly involves the protection of an ethylenediamine derivative with the Boc group, followed by alkylation with an ethyl haloacetate. For instance, ethylenediamine can be reacted with di-tert-butyl dicarbonate (Boc₂O) under controlled conditions to selectively mono-protect one amino group. The resulting Boc-protected ethylenediamine can then be reacted with ethyl bromoacetate or ethyl chloroacetate in the presence of a base to form the desired ester. Alternative synthetic routes might involve the reaction of Boc-protected aminoethylamine with ethyl glycinate derivatives, utilizing various coupling reagents or alkylation strategies.

The compound's utility as a Boc protected amino acid ester makes it a fundamental component in custom peptide synthesis. Researchers often seek to buy this specific intermediate to build complex peptide chains for drug discovery, diagnostics, or material science. Its role as one of the many vital peptide synthesis building blocks ensures that scientific advancements can proceed efficiently. Furthermore, its application extends to general organic synthesis, where it serves as a versatile intermediate for creating various organic molecules. For those in medicinal chemistry, this compound is a valuable starting material for synthesizing potential drug candidates.

NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of sourcing high-quality chemical intermediates. We ensure that compounds like N-[2-(Boc-amino)ethyl]glycine ethyl ester are available to researchers and chemists at competitive price points from reliable suppliers. Understanding the chemical properties and synthesis of such compounds is key to maximizing their potential in scientific endeavors.

In summary, N-[2-(Boc-amino)ethyl]glycine ethyl ester is a compound of significant importance due to its well-defined chemical properties and accessible synthesis. Its role as a crucial intermediate in peptide synthesis and organic chemistry solidifies its position as a valuable reagent for scientific progress.