NINGBO INNO PHARMCHEM CO.,LTD. understands that the successful execution of research in peptide synthesis and drug discovery often hinges on the availability of high-quality, specialized chemical reagents. Fmoc-D-2-Iodophenylalanine is one such compound, and navigating its purchase requires careful consideration of several factors.

Understanding the Compound:

  • Fmoc-D-2-Iodophenylalanine (CAS: 478183-65-2) is a non-natural amino acid derivative crucial for advanced peptide synthesis and medicinal chemistry.
  • It features the Fmoc protecting group, essential for solid-phase peptide synthesis (SPPS), ensuring controlled amino acid addition.
  • The iodine atom at the ortho position of the phenyl ring provides a reactive site for further chemical modifications, such as cross-coupling reactions, enabling the synthesis of complex molecules.

Key Considerations When Purchasing:

  1. Purity and Quality: For any chemical used in sensitive research like peptide synthesis or drug discovery, purity is paramount. Look for suppliers that provide detailed Certificates of Analysis (CoA) specifying the purity level (e.g., by HPLC), molecular weight, and other relevant analytical data. High purity ensures reliable and reproducible experimental results.
  2. Supplier Reputation and Reliability: Choose suppliers with a proven track record in providing specialty chemicals. NINGBO INNO PHARMCHEM CO.,LTD. is committed to quality assurance and customer satisfaction. Consider factors like shipping times, packaging integrity, and customer support when evaluating suppliers.
  3. Pricing and Bulk Orders: The price of Fmoc-D-2-Iodophenylalanine can vary based on purity, quantity, and supplier. For ongoing research projects or larger-scale synthesis, it is often more cost-effective to buy in bulk. Compare prices from multiple reputable vendors, but never compromise on quality for cost savings.
  4. Technical Support and Documentation: A good supplier will offer technical support and readily available documentation, such as Safety Data Sheets (SDS) and technical information. This support can be invaluable when troubleshooting or optimizing synthesis protocols.
  5. Delivery and Shipping: Specialty chemicals often require specific storage and shipping conditions to maintain their integrity. Ensure the supplier can meet these requirements and provides timely delivery.

Applications and Future Research:

Fmoc-D-2-Iodophenylalanine is instrumental in various research areas, including:

  • Peptide Synthesis: Building complex peptide sequences for therapeutic and diagnostic applications.
  • Drug Discovery: Synthesizing novel drug candidates by incorporating unique structural motifs.
  • Bioconjugation: Creating advanced bioconjugates for targeted drug delivery or imaging.
  • Cancer Therapy Research: Developing targeted agents and probes.

By carefully considering these factors when looking to buy Fmoc-D-2-Iodophenylalanine, researchers can secure the essential materials needed to drive their projects forward. Reliable sourcing of such specialized compounds is a critical step in advancing scientific discovery.