Fmoc-Gly-OH, or Fmoc-Glycine, is a compound whose chemical properties are central to its widespread use in advanced chemical synthesis. NINGBO INNO PHARMCHEM CO.,LTD. provides this vital reagent and understands the importance of its inherent characteristics. This exploration delves into the chemical profile of Fmoc-Gly-OH, its stability, and the typical synthesis approaches that make it a reliable choice for researchers.

Chemically, Fmoc-Gly-OH is defined by its molecular formula C17H15NO4 and a molecular weight of approximately 297.31 g/mol. Its structure features a glycine residue protected by the 9-fluorenylmethyloxycarbonyl (Fmoc) group. This protecting group is acid-labile but base-labile, allowing for selective removal during peptide synthesis without affecting other parts of the growing peptide chain. The compound typically appears as a white solid, a characteristic that is crucial for visual confirmation of its form. Its solubility in common organic solvents, particularly Dimethylformamide (DMF), is a key property for its use in solid-phase peptide synthesis (SPPS), where it facilitates smooth reaction kinetics.

The stability of Fmoc-Gly-OH under normal temperatures and pressures is a significant advantage. This stability ensures that the compound can be stored and handled without degradation, maintaining its efficacy over time. When you buy Fmoc-Gly-OH online, knowing it is stable under standard laboratory conditions provides confidence in its performance. The typical melting point of Fmoc-Gly-OH, around 174-175 °C, further indicates its solid, crystalline nature and purity. These physical and chemical attributes make it an ideal amino acid derivative for SPPS and other organic synthesis applications.

The synthesis of Fmoc-Gly-OH typically involves the reaction of glycine with Fmoc-Cl (9-fluorenylmethyloxycarbonyl chloride) or Fmoc-OSu (N-(9-fluorenylmethoxycarbonyloxy)succinimide) under basic conditions. Careful control of reaction parameters, such as pH and temperature, is essential to maximize yield and purity, minimizing side products. NINGBO INNO PHARMCHEM CO.,LTD. employs rigorous synthesis protocols and quality control measures to ensure that the Fmoc-Gly-OH supplied meets the highest standards. This meticulous approach to synthesis underscores our commitment to providing researchers with reliable, high-quality chemical intermediates.

In essence, the well-defined chemical properties and straightforward synthesis of Fmoc-Gly-OH cement its position as a critical building block in organic chemistry. Its stability, solubility, and the protective nature of the Fmoc group make it an indispensable tool for researchers who need to buy Fmoc-Gly-OH online for their demanding synthetic projects.