In the realm of pharmaceutical manufacturing, chemical specifications are the bedrock of quality and consistency. For any intermediate, understanding its detailed chemical profile is paramount to ensuring successful downstream synthesis and regulatory compliance. This is particularly true for 4-Methyl-1H-Pyrrolo[2, 3-D]Pyrimidine (CAS 945950-37-8), a vital component in the synthesis of the JAK inhibitor Ruxolitinib Phosphate.

The CAS number, 945950-37-8, serves as a unique identifier, linking this specific chemical entity across databases and scientific literature. Its molecular formula, C7H7N3, and molecular weight of 133.15 g/mol, define its fundamental chemical identity. However, beyond these basic identifiers, a series of crucial specifications dictate its suitability for pharmaceutical applications.

Purity is one of the most critical specifications. For 4-Methyl-1H-Pyrrolo[2, 3-D]Pyrimidine, a purity level exceeding 98% is typically required. This high level of purity ensures that unwanted side reactions are minimized during the synthesis of Ruxolitinib Phosphate, leading to a cleaner product and higher yields. Analytical techniques like HPLC are employed to verify this purity, ensuring that minimal impurities are present that could affect the final API's safety or efficacy.

Furthermore, the 'Specific Usage' and 'Content Standard' are detailed. This intermediate is noted for its use in 'PRO Analysis' and 'for Synthesis,' indicating its role in both research and development (R&D) and manufacturing. As 'Laboratory Reagents' and 'Analytical Reagents,' it plays a part in quality control and experimental validation.

The source of the material also carries weight. Typically derived through chemical synthesis, understanding the synthesis route itself can offer insights into potential impurities or variations. The 'Source' is listed as 'Synthesis,' which implies a controlled manufacturing process.

Production capacity is another key specification, with figures like '1000kg/Year' indicating the manufacturer's ability to meet commercial demands. This is crucial for pharmaceutical companies planning large-scale production runs.

Certifications such as GMP, ISO 9001, and FDA compliance are not just quality markers; they are prerequisites for pharmaceutical intermediates used in regulated markets. These certifications demonstrate that the intermediate has been produced under conditions that ensure its quality, safety, and traceability throughout the manufacturing process.

In essence, the detailed chemical specifications of intermediates like 4-Methyl-1H-Pyrrolo[2, 3-D]Pyrimidine are a critical part of the pharmaceutical supply chain. They provide the assurance needed for the development and production of safe and effective medicines.