The Chemistry of (S)-2-Aminobutyramide Hydrochloride: Properties and Synthesis Pathways
Delving into the molecular architecture and synthesis of key chemical intermediates is a cornerstone for innovation in the chemical and pharmaceutical industries. (S)-2-Aminobutyramide Hydrochloride, with CAS number 7682-20-4, presents an interesting case study in chiral synthesis and its application as a vital building block. Understanding its fundamental properties and common synthesis pathways allows chemists to effectively utilize and procure this compound.
Physically, (S)-2-Aminobutyramide Hydrochloride is typically characterized as a white to off-white crystalline powder. Its stability and solubility in water and certain organic solvents are key properties that dictate its handling and reaction conditions. The presence of the hydrochloride salt form contributes to its stability and crystalline nature, facilitating easier storage and manipulation compared to its free base form.
The synthesis of (S)-2-Aminobutyramide Hydrochloride usually begins with enantiomerically pure starting materials or involves chiral resolution techniques to isolate the desired (S)-enantiomer. Common routes might involve the transformation of (S)-2-aminobutyric acid or its derivatives. For instance, esterification followed by amidation, or direct amidation of the acid using appropriate activating agents, can yield the amide. Subsequent treatment with hydrochloric acid forms the hydrochloride salt. Ensuring high enantiomeric purity throughout the process is critical.
When professionals seek to buy (S)-2-Aminobutyramide Hydrochloride, they often look for detailed specifications provided by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. These specifications typically include assay (e.g., >99% by HPLC), optical rotation (confirming the (S)-configuration), loss on drying, and residue on ignition, all indicative of the compound's purity and suitability for demanding applications, especially in pharmaceutical intermediate synthesis.
The reactivity of (S)-2-Aminobutyramide Hydrochloride stems from its amine and amide functional groups. The amine group can undergo reactions such as acylation, alkylation, or Schiff base formation, while the amide group can be hydrolyzed or participate in other amide-specific reactions. These functionalities make it a versatile synthon for building more complex molecular structures, including those found in pharmaceuticals and other fine chemicals.
For researchers and manufacturers, identifying reliable sources for chemical building blocks is essential. NINGBO INNO PHARMCHEM CO.,LTD. focuses on providing high-quality chiral intermediates, understanding that consistent chemical properties and purity are the bedrock of successful synthetic outcomes. By offering detailed technical data and ensuring product consistency, they support the rigorous demands of the chemical synthesis community.
In summary, the chemistry of (S)-2-Aminobutyramide Hydrochloride is rich, offering significant utility in various synthetic pathways. Its production requires careful control over stereochemistry and purity. For those involved in chemical synthesis, understanding these aspects ensures the effective application of this valuable chiral intermediate.
Perspectives & Insights
Alpha Spark Labs
“Common routes might involve the transformation of (S)-2-aminobutyric acid or its derivatives.”
Future Pioneer 88
“For instance, esterification followed by amidation, or direct amidation of the acid using appropriate activating agents, can yield the amide.”
Core Explorer Pro
“When professionals seek to buy (S)-2-Aminobutyramide Hydrochloride, they often look for detailed specifications provided by manufacturers like NINGBO INNO PHARMCHEM CO.”