At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on supplying high-caliber chemical compounds that drive innovation. One such compound is N-alpha-Benzyloxycarbonyl-O-benzyl-L-tyrosine (Z-Tyr(Bzl)-OH, CAS: 16677-29-5), a critical amino acid derivative extensively used in peptide synthesis and organic chemistry. This article aims to shed light on its chemical nuances and the value it brings to scientific research.

The structure of Z-Tyr(Bzl)-OH is foundational to its utility. It is a derivative of the amino acid tyrosine, modified with two key protecting groups. The benzyloxycarbonyl (Z) group is attached to the alpha-amino nitrogen, and a benzyl (Bzl) ether is formed with the hydroxyl group on the tyrosine side chain. These protecting groups are essential for controlled synthesis, preventing unwanted side reactions during peptide elongation. When discussing the Z-Tyr(Bzl)-OH wholesale market, consistent quality in these protecting group applications is paramount.

The primary application of Z-Tyr(Bzl)-OH lies in its role as a protecting group in peptide synthesis. In Boc-based SPPS, the Z group provides stable protection for the N-terminus, while the benzyl ether shields the phenolic hydroxyl group of tyrosine. This dual protection ensures that during deprotection steps aimed at removing the Boc group, the tyrosine side chain remains inert. However, it is important to note that under prolonged or harsh acidic conditions for Boc deprotection, some benzyl group migration from the oxygen to the aromatic ring of tyrosine can occur, a factor to consider in long peptide syntheses. This detail underscores the importance of selecting the right amino acid derivative for SPPS.

As an organic synthesis intermediate, Z-Tyr(Bzl)-OH offers a pre-functionalized tyrosine moiety that can be incorporated into more complex molecular architectures. Chemists utilize such building blocks to efficiently assemble target molecules in various fields, including medicinal chemistry and material science. The availability of high-purity organic synthesis intermediate compounds is crucial for reproducible results.

The compound is also valued as a biochemical reagent, enabling researchers to study biological processes involving tyrosine residues or to synthesize modified peptides for research purposes. The demand for specialized biochemical reagent compounds is consistently high in academic and industrial research settings. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier of Z-Tyr(Bzl)-OH, offering competitive pricing and reliable delivery.

For those seeking to purchase Z-Tyr(Bzl)-OH, understanding the various applications and the source of the material is vital. The Z-Tyr(Bzl)-OH price is influenced by purity, scale, and manufacturing standards. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing excellent value, ensuring that researchers have access to this essential compound for their work. As a leading manufacturer of Z-Tyr(Bzl)-OH, we ensure that every batch meets stringent quality controls.