The pharmaceutical industry places immense importance on the purity of its products. For drugs like Amitriptyline, a widely prescribed antidepressant, understanding and controlling impurities is a critical aspect of quality assurance. Dibenzosuberone (CAS: 1210-35-1) plays a pivotal role in this process, acting as both a synthetic precursor and a key impurity reference standard.

Dibenzosuberone, chemically known as 10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-one, is intrinsically linked to Amitriptyline through its role in synthesis. As a pharmaceutical intermediate, it is used in the chemical pathways that lead to the formation of Amitriptyline. This relationship means that Dibenzosuberone itself can potentially be present as a residual starting material or a degradation product in the final Amitriptyline formulation.

Consequently, Dibenzosuberone is indispensable as an Amitriptyline impurity reference standard. Pharmaceutical quality control laboratories use certified Dibenzosuberone to develop and validate analytical methods, such as chromatography, to detect and quantify its presence in Amitriptyline samples. This ensures that the drug product meets stringent regulatory limits for impurities. The accuracy of these analytical procedures relies on a thorough understanding of the CAS 1210-35-1 chemical properties, ensuring reliable comparisons.

The process of analytical method development with Dibenzosuberone involves carefully optimizing parameters to achieve adequate separation and detection of this compound from the main API and other potential impurities. High-purity Dibenzosuberone, as supplied by NINGBO INNO PHARMCHEM CO.,LTD., is essential for the accuracy and reproducibility of these methods. This ensures that the final Amitriptyline product is safe and effective for patient use.

The meticulous control over impurities, facilitated by reference standards like Dibenzosuberone, is a testament to the pharmaceutical industry's commitment to patient safety and product quality. By providing reliable pharmaceutical intermediates and reference standards, companies like NINGBO INNO PHARMCHEM CO.,LTD. contribute significantly to the integrity of the drug supply chain, ensuring that essential medications are produced to the highest standards.