Exploring the Chemical Properties and Synthesis of Dibenzyl Ketoxime
Dibenzyl Ketoxime, also known by its CAS number 1788-31-4, is a fascinating organic compound that holds considerable utility in various chemical applications, especially as an intermediate in organic synthesis. Understanding its fundamental chemical properties and the nuances of its synthesis is crucial for chemists aiming to leverage its full potential in research and development.
The molecular formula of Dibenzyl Ketoxime is C₁₅H₁₅NO, with a molecular weight of approximately 225.29 g/mol. Its physical appearance is typically described as a white or pale yellow crystalline powder. Key properties include a melting point range of 122–124°C and a boiling point of 407.8°C at 760 mmHg. It exhibits limited solubility in water due to its hydrophobic phenyl groups but dissolves readily in many organic solvents. The presence of the oxime functional group (C=N-OH) confers specific reactivity, allowing it to participate in a variety of chemical transformations, such as reduction, oxidation, and rearrangement reactions. These characteristics make Dibenzyl Ketoxime a valuable reagent for synthetic chemists.
The synthesis of Dibenzyl Ketoxime is primarily achieved through the oximation of dibenzyl ketone. This process generally involves reacting dibenzyl ketone with hydroxylamine or its salts, such as hydroxylamine hydrochloride. The reaction is typically carried out in a suitable solvent, often in the presence of a base to neutralize any acid generated. Optimizing reaction conditions, including temperature, reaction time, and the choice of base and solvent, is critical for achieving high yields and purity. Industrial production methods often focus on efficiency and scalability, sometimes employing specific patented processes to maximize output and minimize byproducts. For researchers looking to buy Dibenzyl Ketoxime, understanding these synthesis pathways can provide insight into the quality and consistency of the product available on the market.
The compound's reactivity is a key aspect of its utility. For instance, Dibenzyl Ketoxime can be reduced using agents like lithium aluminum hydride to yield amines, a common transformation in the synthesis of pharmaceutical compounds. It can also undergo Beckmann rearrangement under catalytic conditions to form amides or nitriles. These reactions highlight its versatility as a building block. The detailed understanding of these dibenzyl ketoxime properties allows chemists to design targeted synthetic routes for complex molecules. Whether for academic research or industrial application, reliable access to this chemical is essential. Sourcing from reputable suppliers of Dibenzyl Ketoxime ensures that researchers can obtain material that meets rigorous purity standards required for experimental success.
The exploration of Dibenzyl Ketoxime continues, with ongoing research investigating its potential applications and reactivity. Its role as a pharmaceutical intermediate remains prominent, but its biological activities are also becoming a focus of scientific inquiry. For those seeking to procure this compound, companies like NINGBO INNO PHARMCHEM CO.,LTD offer Dibenzyl Ketoxime, supporting the needs of the scientific community with quality chemical products.
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