At Ningbo Inno Pharmchem Co., Ltd., we are committed to providing comprehensive information on the chemicals we supply. Methyl 4-bromo-1H-indole-2-carboxylate (CAS 167479-13-2) is a notable example, prized for its distinctive chemical profile and utility in advanced organic synthesis. Understanding its core properties is crucial for leveraging its full potential in research and development.

The compound's chemical structure is characterized by an indole ring, a bromine substituent at the 4-position, and a methyl ester at the 2-position. This arrangement imparts specific reactivity, making it an excellent substrate for various synthetic transformations. Key physical properties include a reported boiling point of 386.2°C at 760 mmHg and a flash point of 187.3°C, indicating its stability under typical laboratory conditions. The density is recorded at 1.629 g/cm³. Purity levels of 95%min are standard for this intermediate, ensuring reliable performance in subsequent reactions.

The methyl 4-bromo-1h-indole-2-carboxylate synthesis is a critical aspect for its widespread application. Efficient and scalable synthetic routes are essential to meet the demands of the chemical industry. Researchers often employ methods that capitalize on the indole core's inherent reactivity, such as electrophilic substitution or transition metal-catalyzed coupling reactions. The presence of the bromine atom, for instance, makes it an ideal candidate for Suzuki, Heck, or Sonogashira couplings, enabling the introduction of diverse aryl, vinyl, or alkynyl groups.

These synthetic capabilities directly translate into the broad methyl 4-bromo-1h-indole-2-carboxylate applications. As a fundamental component within organic synthesis building blocks, it facilitates the creation of complex heterocyclic systems that are prevalent in pharmaceuticals, agrochemicals, and advanced materials. The unique combination of the indole scaffold and the reactive bromine atom makes it particularly useful in constructing molecules with potential biological activity or specific electronic properties.

The importance of the CAS number 167479-13-2 cannot be overstated, as it ensures unambiguous identification of this versatile chemical. Ningbo Inno Pharmchem Co., Ltd. prioritizes the quality and consistency of this compound, understanding its vital role in our clients' research pipelines. We are dedicated to supporting scientific advancement by providing reliable access to essential chemical intermediates that drive innovation.