Boronic acids represent a powerful class of organic compounds, renowned for their versatile synthetic utility and their crucial roles in catalysis, materials science, and pharmaceuticals. Among these, arylboronic acids, such as 4-Bromobenzeneboronic acid (CAS 5467-74-3), stand out due to their prevalence in cross-coupling reactions. NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of these essential compounds, offering high-purity materials like our 4-Bromobenzeneboronic acid to support diverse scientific and industrial endeavors.

The synthesis of arylboronic acids typically involves the reaction of an aryl Grignard or aryl lithium reagent with a trialkyl borate, followed by acidic hydrolysis. Alternatively, direct borylation of aromatic compounds can also be employed. The resulting boronic acid group (-B(OH)2) is key to their reactivity. In the case of 4-Bromobenzeneboronic acid, the presence of both the bromine atom and the boronic acid group on the benzene ring creates a bifunctional molecule with distinct synthetic pathways.

The most significant application of 4-Bromobenzeneboronic acid lies in its participation in the Suzuki-Miyaura cross-coupling reaction. This Nobel Prize-winning methodology allows for the formation of C-C bonds between aryl halides (like the bromo-substituted part of our compound) and organoboron compounds (like the boronic acid part itself, or other arylboronic acids). This reaction is fundamental to the synthesis of complex organic molecules, including advanced OLED materials and pharmaceutical intermediates. The ability to buy 4-Bromobenzeneboronic acid with high purity ensures predictable and efficient coupling outcomes, crucial for building intricate molecular architectures.

Beyond Suzuki couplings, boronic acids can undergo other transformations, such as Chan-Lam coupling (forming C-N and C-O bonds) and can act as directing groups or catalysts in certain reactions. The specific properties of 4-Bromobenzeneboronic acid, including its solubility in methanol and its solid, off-white powder form, make it convenient to handle and integrate into various synthetic protocols. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our high purity boronic acid offerings meet the rigorous demands of modern research laboratories and manufacturing facilities.

As a key organic synthesis building block, 4-Bromobenzeneboronic acid empowers chemists to design and create novel materials and therapeutic compounds. We are committed to facilitating these advancements by providing reliable access to this essential chemical, thereby supporting innovation across multiple scientific disciplines.