In the realm of fine chemicals and pharmaceutical intermediates, a thorough understanding of a compound's physical and chemical properties is not just academic; it's fundamental to successful manufacturing and research. 2-Amino-5-bromopyrimidine (CAS 7752-82-1) is a prime example, where its specific characteristics directly dictate its utility, particularly in the demanding field of API synthesis.

The core identity of 2-Amino-5-bromopyrimidine is defined by its molecular formula C4H4BrN3 and a molecular weight of 173.999. Physically, it presents as a yellow powder, a key identifier for quality control. Its thermal properties are also significant: a boiling point of 340.7 ± 34.0 °C at 760 mmHg and a melting point of 241-243 °C (lit.) indicate a relatively stable solid under standard conditions. The density of 1.8 ± 0.1 g/cm³ further contributes to its material handling profile. These detailed chemical properties of 2-Amino-5-bromopyrimidine are crucial for process engineers and chemists who design and execute synthetic routes.

The primary application driving demand for this compound is its role as a precursor in the Macitentan synthesis. The precise arrangement of atoms and functional groups within 2-Amino-5-bromopyrimidine makes it an ideal starting point for building the complex structure of Macitentan. The reliability of its CAS 7752-82-1 pharmaceutical intermediate status hinges on these intrinsic properties. When pharmaceutical companies seek to buy 2-Amino-5-bromopyrimidine supplier, they are essentially looking for a partner who can consistently deliver this compound with these specified characteristics.

The understanding of these properties also aids in optimizing the synthesis of macitentan precursor. For instance, knowing the melting point helps in designing crystallization and purification steps, while the density is relevant for volume calculations in large-scale production. The assay of ≥98.0% further reinforces the expectation of a high-quality, well-defined chemical entity.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity intermediates like 2-Amino-5-bromopyrimidine, backed by a thorough understanding of its critical chemical properties. We aim to empower our clients in the pharmaceutical industry by supplying reliable building blocks that facilitate efficient and successful API synthesis, thereby contributing to the development of essential medicines.

Keywords: Chemical Properties 2-Amino-5-bromopyrimidine, API Synthesis, Macitentan Precursor, CAS 7752-82-1, Pharmaceutical Intermediate, Organic Chemistry, NINGBO INNO PHARMCHEM CO.,LTD.