Sildenafil Citrate Synthesis: The Role of 4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide
The pharmaceutical industry's commitment to producing high-quality medicines necessitates a deep understanding of the chemical synthesis pathways involved. For Sildenafil Citrate, a well-known drug, the process relies on a series of precisely manufactured intermediates. Among these, 4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide, identified by CAS number 139756-03-9, stands out as a critical component. NINGBO INNO PHARMCHEM CO.,LTD. is a key player in supplying this vital chemical intermediate.
The compound, chemically known as 4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide, with the molecular formula C17H22N4O3 and a molecular weight of 330.38, is a cornerstone in the multi-step synthesis of Sildenafil Citrate. Its specific structure and purity are essential for achieving the desired end-product. Pharmaceutical manufacturers carefully manage the 4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide synthesis to ensure optimal yield and minimal impurities, thereby enhancing the overall efficiency of Sildenafil production. The consistent quality of such Sildenafil intermediate chemicals is a major factor in drug manufacturing success.
Beyond its primary role in synthesis, this compound also functions as a vital pharmaceutical impurity reference standard. Analytical laboratories utilize it to develop and validate sophisticated methods for quality control, ensuring that batches of Sildenafil Citrate meet stringent purity specifications. The precise identification of impurities, facilitated by reference standards, is crucial for regulatory compliance and patient safety. The detailed chemical properties of 139756-03-9 are therefore of great importance to quality assurance professionals.
For companies engaged in pharmaceutical development and manufacturing, securing a reliable supplier for essential intermediates is paramount. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality 4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide, supporting the industry's need for consistent and pure chemical inputs. Understanding the various 4-(2-ethoxybenzamido)-1-methyl-3-n-propylpyrazole-5-carboxamide applications, especially in analytical and synthetic contexts, enables pharmaceutical companies to maintain the highest standards in their production processes.
Perspectives & Insights
Future Origin 2025
“Beyond its primary role in synthesis, this compound also functions as a vital pharmaceutical impurity reference standard.”
Core Analyst 01
“Analytical laboratories utilize it to develop and validate sophisticated methods for quality control, ensuring that batches of Sildenafil Citrate meet stringent purity specifications.”
Silicon Seeker One
“The precise identification of impurities, facilitated by reference standards, is crucial for regulatory compliance and patient safety.”