The Chemical Identity and Properties of 2-Chloro-5-(trifluoromethyl)phenol
Understanding the precise chemical identity and properties of building blocks is fundamental to successful synthesis in chemistry. 2-Chloro-5-(trifluoromethyl)phenol, a key compound supplied by NINGBO INNO PHARMCHEM CO.,LTD., offers a fascinating case study in molecular design and utility. Its chemical structure, C7H4ClF3O, reveals a benzene ring substituted with a hydroxyl group (-OH), a chlorine atom (-Cl), and a trifluoromethyl group (-CF3). This specific arrangement dictates its reactivity and potential applications across various scientific disciplines.
Physically, 2-Chloro-5-(trifluoromethyl)phenol is characterized as a light yellow oily liquid. Its molecular weight is approximately 196.55 g/mol. The presence of the trifluoromethyl group significantly influences its properties, often increasing lipophilicity and altering electronic characteristics compared to its non-fluorinated counterparts. For instance, the refractive index and density are important parameters for quality control and formulation, with values typically around 1.473 and 1.459 g/mL, respectively. These detailed specifications are crucial for researchers seeking an organic synthesis intermediate that meets exact requirements.
The compound's reactivity stems from the interplay of its functional groups. The phenolic hydroxyl group can participate in reactions like esterification or etherification, while the chlorine atom and the trifluoromethyl group influence the aromatic ring's reactivity towards electrophilic or nucleophilic substitution. This makes it a versatile organic synthesis building block, capable of being transformed into a wide array of more complex molecules. The stability of the C-F bonds in the trifluoromethyl group generally ensures that this portion of the molecule remains intact during many synthetic transformations.
As a pharmaceutical intermediate precursor and an agrochemical development chemical, its properties are leveraged to create compounds with specific biological activities. For example, increased lipophilicity can aid in cell membrane penetration, a key factor in both drug efficacy and pesticide action. When considering its purchase, clients rely on suppliers like NINGBO INNO PHARMCHEM CO.,LTD. for accurate technical data and consistent product quality. The meticulous synthesis and purification processes ensure that the chemical is a reliable component for demanding applications in research and industrial production, making it an invaluable specialty chemical for innovation.
Perspectives & Insights
Quantum Pioneer 24
“This specific arrangement dictates its reactivity and potential applications across various scientific disciplines.”
Bio Explorer X
“Physically, 2-Chloro-5-(trifluoromethyl)phenol is characterized as a light yellow oily liquid.”
Nano Catalyst AI
“The presence of the trifluoromethyl group significantly influences its properties, often increasing lipophilicity and altering electronic characteristics compared to its non-fluorinated counterparts.”