The Chemical Profile of 1-Phenylpiperidine: Properties and Handling for Researchers
For researchers and chemists working with organic compounds, a thorough understanding of a substance's chemical profile is crucial for successful experimentation and safe handling. 1-Phenylpiperidine (CAS: 4096-20-2) is one such compound whose properties are well-documented, making it a reliable component in various synthetic pathways and analytical procedures.
The typical appearance of 1-Phenylpiperidine is a white powder, although it can also be encountered as a colorless to slightly yellow or orange clear liquid depending on its purity and storage conditions. Its molecular formula, C11H15N, and molecular weight of 161.25 g/mol define its basic chemical identity. The purity of commercially available 1-Phenylpiperidine is generally high, often specified as ≥98.0% by Gas Chromatography (GC), ensuring that it is suitable for demanding chemical reactions where impurities could lead to unwanted side products or reduced yields.
Key physical properties that are important for researchers include its boiling point, which is approximately 258°C at atmospheric pressure, and its refractive index, often cited around n20D 1.56. The flash point of 106.1°C indicates a moderate flammability risk, necessitating appropriate safety precautions during handling and storage. Melting point data also exists, with some sources noting a melting point of 4.70°C for the pure compound, reinforcing its tendency to exist as a liquid at room temperature.
Proper storage is vital for maintaining the quality and integrity of 1-Phenylpiperidine. It is recommended to store the compound in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances. This practice helps prevent degradation and contamination, ensuring its efficacy for future use. Understanding these storage requirements is part of safe laboratory practice and is often detailed in the Safety Data Sheets (SDS) provided by suppliers.
The safe handling of 1-Phenylpiperidine also involves adherence to standard laboratory safety protocols. While specific hazard statements may vary slightly between suppliers, common warnings include potential skin and eye irritation, and respiratory tract irritation. Researchers are advised to wear appropriate personal protective equipment (PPE), such as gloves, safety glasses, and lab coats, and to work in a well-ventilated fume hood. Access to and review of the product's SDS is a fundamental step before commencing any work with the compound.
In summary, 1-Phenylpiperidine is a well-characterized organic compound with a valuable set of properties for chemical synthesis and research. Its consistent appearance, high purity, and defined physical characteristics, coupled with clear handling and storage guidelines, make it a dependable resource for scientists across various disciplines. Adhering to these guidelines ensures both the success of experiments and the safety of laboratory personnel.
Perspectives & Insights
Alpha Spark Labs
“While specific hazard statements may vary slightly between suppliers, common warnings include potential skin and eye irritation, and respiratory tract irritation.”
Future Pioneer 88
“Researchers are advised to wear appropriate personal protective equipment (PPE), such as gloves, safety glasses, and lab coats, and to work in a well-ventilated fume hood.”
Core Explorer Pro
“Access to and review of the product's SDS is a fundamental step before commencing any work with the compound.”