Understanding the detailed chemical and physical properties of a compound is fundamental for its effective and safe utilization in synthesis. (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, identified by its CAS number 147126-62-3, is a prime example of such a crucial intermediate in the pharmaceutical industry. This compound is primarily recognized for its role in the production of antiviral drugs.

Chemically, this molecule is a chiral ester with a distinct oxathiolane ring structure. Its molecular formula is C14H24O4S, and it has a molecular weight of approximately 288.40 g/mol. The compound is typically described as a white to off-white powder. Its melting point usually falls within the range of 93-101°C, indicating a stable solid form at room temperature. Key physical properties such as density are noted around 1.16, and its refractive index is approximately 1.527. These properties are vital for quality control and process development.

When considering the storage and handling of this intermediate, adherence to safety guidelines is paramount. Information from Material Safety Data Sheets (MSDS) and Globally Harmonized System (GHS) classifications provides essential safety data. It is often advised to store the product in a cool, well-ventilated place, sealed from moisture and light, typically at temperatures between 2-8°C. The GHS pictograms often associated with this compound include 'Warning,' with hazard statements such as H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Corresponding precautionary statements guide safe handling practices.

The significance of (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester lies in its specific stereochemistry, which is critical for its function as an intermediate. Its precise structure enables it to be efficiently converted into the active pharmaceutical ingredients of Lamivudine and Emtricitabine. The ability to reliably source this specific enantiomer is a testament to advancements in chiral synthesis and purification techniques, a field where NINGBO INNO PHARMCHEM CO.,LTD. excels.

For researchers and manufacturers, understanding these properties is crucial for optimizing reaction conditions, predicting solubility, and ensuring safe laboratory or industrial practices. The continuous research into its applications further highlights its importance in the broader field of organic synthesis and medicinal chemistry. By focusing on the chemical profile, businesses can ensure they are obtaining and handling this key intermediate with the utmost care and efficiency.

In summary, (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (CAS 147126-62-3) is a well-characterized compound with specific physical and chemical properties that dictate its application and handling. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this vital intermediate with detailed technical specifications and safety information, supporting its critical role in the pharmaceutical industry.