The Chemical Properties and Safety of 4-Hydroxyphenylacetamide Explained
At NINGBO INNO PHARMCHEM CO., LTD., we understand that detailed knowledge of a chemical's properties and safety is crucial for its effective and responsible use. This article provides an overview of 4-Hydroxyphenylacetamide (CAS 17194-82-0), focusing on its chemical characteristics and safety aspects.
Physically, 4-Hydroxyphenylacetamide typically presents as a beige to off-white crystalline powder. Its melting point is generally recorded in the range of 168-172°C, indicating a stable solid form under normal conditions. Solubility is a key property; it is described as slightly soluble in water but more soluble in organic solvents like ethanol and DMSO. These characteristics are important for its handling and application in various synthesis processes.
Chemically, 4-Hydroxyphenylacetamide possesses a molecular formula of C8H9NO2 and a molecular weight of approximately 151.16 g/mol. The presence of the phenolic hydroxyl group and the acetamide moiety contributes to its reactivity, making it a valuable intermediate in organic synthesis. Its pKa value is predicted to be around 9.99 ± 0.26, indicating its weakly acidic nature.
Safety information for 4-Hydroxyphenylacetamide highlights it as an irritant. Hazard statements commonly include H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Consequently, appropriate precautionary measures must be taken during handling. These include wearing suitable protective clothing, gloves, and eye/face protection (P280). In case of contact, immediate rinsing with plenty of water is advised (P305+P351+P338 for eyes, P302+P352 for skin). Good ventilation is also recommended when working with the substance (P271).
Storage conditions are also important for maintaining the integrity of 4-Hydroxyphenylacetamide. It should be stored at room temperature in an airtight container, protected from light and moisture. These measures help to prevent degradation and ensure its suitability for downstream applications. NINGBO INNO PHARMCHEM CO., LTD. adheres to strict storage protocols to deliver products of the highest quality.
As a responsible supplier, NINGBO INNO PHARMCHEM CO., LTD. ensures that all necessary safety data sheets (SDS) are available for its products, providing comprehensive guidance for safe handling, storage, and emergency procedures. Our commitment to product stewardship means we prioritize the safety and well-being of our customers and the environment.
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“These measures help to prevent degradation and ensure its suitability for downstream applications.”
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“ensures that all necessary safety data sheets (SDS) are available for its products, providing comprehensive guidance for safe handling, storage, and emergency procedures.”
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“Our commitment to product stewardship means we prioritize the safety and well-being of our customers and the environment.”