The Chemistry of Chiral Building Blocks: Exploring [(2S)-1-Ethylpyrrolidin-2-yl]methanamine
The field of organic chemistry is continuously enriched by the exploration of novel molecular structures and their applications. Among these, chiral building blocks stand out due to their unique stereochemical properties, which are fundamental to the development of advanced materials and pharmaceuticals. A prime example of such a crucial component is [(2S)-1-ethylpyrrolidin-2-yl]methanamine, bearing the CAS number 22795-99-9. This molecule, characterized by its pyrrolidine ring and an aminomethyl substituent, is a testament to the precision achievable in modern chemical synthesis.
With a molecular formula of C7H16N2 and a molecular weight of 128.22, [(2S)-1-ethylpyrrolidin-2-yl]methanamine presents itself as a clear, colorless to faintly yellow liquid. Its physical properties, including a boiling point of 50-52 °C (lit.) and a refractive index of n20/D 1.4670 (lit.), provide essential data for handling and processing. The compound's optical activity, with specific rotation values typically around -107º (c=1, methanol), confirms its chiral nature, a characteristic that dictates its utility in stereoselective reactions. Its solubility in common organic solvents like chloroform and methanol, contrasted with slight solubility in water, further defines its behavior in various chemical environments.
The primary application of [(2S)-1-ethylpyrrolidin-2-yl]methanamine lies in its role as a pharmaceutical intermediate. It is a key precursor in the synthesis of Levonsulpiride, an established medication. Beyond this, its reactive amine functional group and chiral center make it a valuable reagent for a broad spectrum of organic synthesis endeavors, aiding researchers in constructing complex molecular architectures. Understanding these chemical properties is vital for chemists aiming to leverage this molecule in new synthesis pathways or to optimize existing ones.
For those seeking to acquire this valuable building block, the availability from manufacturers in China, like NINGBO INNO PHARMCHEM CO., LTD., offers a competitive edge in terms of cost and accessibility. The ability to buy (2S)-1-ethylpyrrolidin-2-yl]methanamine with guaranteed quality and purity from reliable suppliers is essential for both research institutions and large-scale manufacturing operations. Exploring the chemistry of such chiral building blocks opens up new possibilities in drug discovery and the development of fine chemicals.
Perspectives & Insights
Quantum Pioneer 24
“Understanding these chemical properties is vital for chemists aiming to leverage this molecule in new synthesis pathways or to optimize existing ones.”
Bio Explorer X
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Nano Catalyst AI
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