The Crucial Role of Ethyl 2,4,5-Trifluorobenzoylacetate in Antibiotic Synthesis
In the intricate world of pharmaceutical manufacturing, the selection of high-quality intermediates is paramount to the success of drug synthesis. Ethyl 2,4,5-Trifluorobenzoylacetate, a compound identified by the CAS number 98349-24-7, has emerged as a critical component in the production of vital medications. Its unique chemical structure and purity make it an indispensable precursor, particularly in the synthesis of the broad-spectrum antibiotic, Delafloxacin.
Delafloxacin is a fluoroquinolone antibiotic known for its efficacy against a range of Gram-positive and Gram-negative bacteria, including difficult-to-treat strains like Methicillin-resistant Staphylococcus aureus (MRSA). The intricate multi-step synthesis of Delafloxacin relies heavily on precise chemical intermediates, and Ethyl 2,4,5-Trifluorobenzoylacetate plays a pivotal role in establishing the core structure necessary for the final active pharmaceutical ingredient (API). Understanding the ethyl 2,4,5-trifluorobenzoylacetate synthesis is key for efficient drug development.
The compound, characterized as a white powder with a purity of u226599.0%, boasts a molecular formula of C11H9F3O3 and a molecular weight of 246.183. Its physical and chemical properties, such as its density of approximately 1.3 g/cmu00b3 and a boiling point of around 283.1 u00b0C at 760 mmHg, are well-documented, providing essential data for process chemists. The delafloxacin intermediate preparation requires strict adherence to these specifications to ensure the quality and yield of the final product.
The importance of sourcing reliable CAS 98349-24-7 chemical properties cannot be overstated. Manufacturers and researchers involved in developing new antibiotics or improving existing synthesis routes often seek out these specialized fluorochemicals. The pharmaceutical applications of Ethyl 2,4,5-Trifluorobenzoylacetate are primarily centered around its role as a precursor, highlighting its value in the pharmaceutical supply chain. The availability of high purity ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate directly impacts the efficiency and cost-effectiveness of producing critical antibiotics.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality chemical intermediates that meet the stringent demands of the pharmaceutical industry. By ensuring the availability of compounds like Ethyl 2,4,5-Trifluorobenzoylacetate, we aim to support advancements in drug discovery and manufacturing, ultimately contributing to better healthcare outcomes worldwide.
Perspectives & Insights
Silicon Analyst 88
“Manufacturers and researchers involved in developing new antibiotics or improving existing synthesis routes often seek out these specialized fluorochemicals.”
Quantum Seeker Pro
“The pharmaceutical applications of Ethyl 2,4,5-Trifluorobenzoylacetate are primarily centered around its role as a precursor, highlighting its value in the pharmaceutical supply chain.”
Bio Reader 7
“The availability of high purity ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate directly impacts the efficiency and cost-effectiveness of producing critical antibiotics.”