The Role of (3S,5S)-3,5-Bis(tert-butyldimethylsilyloxy)cyclohexanone in Modern Pharmaceutical Synthesis
At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to advancing the field of chemical synthesis by providing high-quality intermediates. One such vital compound is (3S,5S)-3,5-Bis(tert-butyldimethylsilyloxy)cyclohexanone, identified by CAS 139356-35-7. This molecule plays a crucial role as a pharmaceutical intermediate, particularly in the complex synthesis pathways leading to vital therapeutic agents like Paricalcitol (CAS: 131918-61-1).
The chemical structure of (3S,5S)-3,5-Bis(tert-butyldimethylsilyloxy)cyclohexanone features silyloxy protecting groups strategically placed on the cyclohexanone ring. These protecting groups are indispensable in multi-step organic synthesis, as they shield reactive hydroxyl functionalities from unwanted reactions during critical stages of a chemical transformation. This allows chemists to perform specific modifications on other parts of the molecule with greater control and precision. When we discuss the synthesis of Paricalcitol, the use of such protected intermediates is not merely a convenience; it is a necessity for achieving the desired stereochemistry and purity of the final active pharmaceutical ingredient (API).
The demand for reliable Paricalcitol synthesis intermediates highlights the importance of compounds like ours. By utilizing (3S,5S)-3,5-bis(tert-butyl-dimethyl-silanyloxy)-cyclohexanone, manufacturers can expect improved yields and a more streamlined production process. The specific stereochemistry, denoted by (3S,5S), is also a critical factor. In pharmaceutical synthesis, the three-dimensional arrangement of atoms within a molecule can drastically affect its biological activity and efficacy. Therefore, sourcing intermediates with the correct chiral configuration is paramount. Our commitment to high purity ensures that any impurities are minimized, thereby reducing potential side reactions and simplifying downstream purification steps. This focus on quality is what distinguishes NINGBO INNO PHARMCHEM CO.,LTD. in the market for specialty pharmaceutical intermediates.
For companies looking to buy or purchase this essential chemical, understanding its properties and applications is key. The CAS 139356-35-7 chemical properties are well-documented, allowing for effective integration into existing synthetic protocols. The compound serves as a perfect example of how advanced organosilicon chemistry contributes to the pharmaceutical industry. We offer this silyloxy protected cyclohexanone in various packaging options, including 25kg cardboard drums, or tailored to specific customer requirements, ensuring seamless logistics and integration into your manufacturing workflow. Partner with NINGBO INNO PHARMCHEM CO.,LTD. for your critical pharmaceutical intermediate needs, and experience the difference that quality and expertise can make.
Perspectives & Insights
Logic Thinker AI
“The compound serves as a perfect example of how advanced organosilicon chemistry contributes to the pharmaceutical industry.”
Molecule Spark 2025
“We offer this silyloxy protected cyclohexanone in various packaging options, including 25kg cardboard drums, or tailored to specific customer requirements, ensuring seamless logistics and integration into your manufacturing workflow.”
Alpha Pioneer 01
“for your critical pharmaceutical intermediate needs, and experience the difference that quality and expertise can make.”