The Role of 7-Hydroxy-1-tetralone in Modern Drug Discovery
NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the significant contributions of 7-Hydroxy-1-tetralone (CAS: 22009-38-7) to the field of drug discovery and development. This versatile chemical compound, also known by its CAS number, is more than just a pharmaceutical intermediate; it's a foundational element in the creation of innovative therapies. Its unique structure and reactivity make it an indispensable tool for researchers aiming to synthesize novel drug candidates.
One of the primary applications of 7-Hydroxy-1-tetralone lies in its role as a critical building block. It is instrumental in the synthesis of widely used pharmaceuticals, notably sertraline, a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for depression and anxiety disorders. The intricate synthesis of such drugs relies on precise chemical transformations, and 7-Hydroxy-1-tetralone provides the essential structural framework. Furthermore, its involvement in the synthesis of potent opioid analgesics like (-)-dezocine underscores its importance in pain management research.
Beyond its utility as a synthetic precursor, 7-Hydroxy-1-tetralone and its derivatives exhibit fascinating biological activities that are actively being investigated. A significant area of research focuses on their potential as Monoamine Oxidase (MAO) inhibitors. MAO enzymes play a crucial role in the metabolism of key neurotransmitters such as serotonin and dopamine. By inhibiting these enzymes, compounds derived from 7-Hydroxy-1-tetralone can modulate neurotransmitter levels in the brain, offering therapeutic potential for conditions like Parkinson's disease and depression. The ability to fine-tune these effects through structural modifications makes it a prime candidate for further drug development in neuroscience.
Moreover, the compound's potential extends into oncology and infectious disease research. Studies have indicated that certain tetralone derivatives possess anticancer properties, demonstrating cytotoxic effects against various cancer cell lines and even showing synergistic activity when combined with agents like Vitamin D3. This combined effect is thought to be mediated by the inhibition of specific enzymes that regulate cell growth and differentiation. In the realm of infectious diseases, derivatives have also shown promise as antimicrobial agents, exhibiting activity against a range of fungal and bacterial pathogens. This broad biological activity profile highlights the compound's adaptability and potential for diverse therapeutic applications.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying high-quality 7-Hydroxy-1-tetralone to researchers and pharmaceutical companies worldwide. Understanding the crucial role of this compound, we ensure purity and reliability in our products. The ongoing exploration of 7-Hydroxy-1-tetralone's drug discovery capabilities, from its fundamental role as a chemical building block to its direct biological interactions, continues to pave the way for significant advancements in modern medicine.
Perspectives & Insights
Chem Catalyst Pro
“This broad biological activity profile highlights the compound's adaptability and potential for diverse therapeutic applications.”
Agile Thinker 7
“is committed to supplying high-quality 7-Hydroxy-1-tetralone to researchers and pharmaceutical companies worldwide.”
Logic Spark 24
“Understanding the crucial role of this compound, we ensure purity and reliability in our products.”