NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the significant role of D-Serine in modern pharmaceutical manufacturing, particularly in the synthesis of Lacosamide. As a crucial intermediate, D-Serine's quality and purity directly impact the efficacy and safety of the final drug product. Understanding the chemical properties and specifications of D-Serine is paramount for any pharmaceutical company engaged in its procurement and utilization.

D-Serine, with its CAS number 312-84-5, is characterized by its appearance as a white crystalline powder. Its molecular formula is C3H7NO3, and it has a molecular weight of 105.093. The pharmaceutical industry demands stringent quality control, and D-Serine typically meets these needs with an assay of ≥98.0%. Furthermore, its specific rotation, usually between -14.5° and -15.5°, is a critical indicator of its chiral integrity. This chiral purity, often specified as ≥99.5%, is essential for enantioselective synthesis, a cornerstone of modern drug development. Low moisture content (≤0.25%) and minimal heavy metal contamination (≤10ppm) are also key specifications that ensure the material is suitable for pharmaceutical applications.

The primary application driving the demand for high-purity D-Serine is its use as an intermediate in the synthesis of Lacosamide. Lacosamide, marketed under brand names such as Vimpat, is an anticonvulsant medication used to treat partial-onset seizures and primary generalized tonic-clonic seizures. The synthesis of Lacosamide involves multiple steps where the precise molecular structure and chirality of D-Serine are leveraged to produce the desired enantiomer of the final drug. Various patented processes focus on optimizing the Lacosamide synthesis from D-serine, aiming for higher yields, reduced costs, and improved environmental profiles. For companies looking to buy D-serine for lacosamide synthesis, it is crucial to partner with a reliable CAS 312-84-5 D-serine supplier who can consistently provide material meeting these exacting standards.

The chemical synthesis pathways for Lacosamide often begin with D-serine and involve steps such as N-protection, coupling with benzylamine, O-methylation, and N-acetylation. Each of these steps requires carefully controlled conditions and high-purity reagents. The ability to source D-serine with guaranteed D-serine chiral purity specifications is non-negotiable for manufacturers aiming for an efficient and reproducible production process. NINGBO INNO PHARMCHEM CO.,LTD. understands these demands and is committed to supplying D-Serine that adheres to the highest industry benchmarks, facilitating the successful production of vital medicines like Lacosamide.