The Significance of 4-Bromo-2-iodopyridine in Developing Treatments for PARP-1 Associated Diseases
At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying the chemical building blocks that drive medical progress. Today, we focus on 4-Bromo-2-iodopyridine (CAS: 100523-83-9), a vital compound in the development of treatments for diseases linked to the Poly(ADP-ribose)polymerase-1 (PARP-1) enzyme.
PARP-1 is a crucial enzyme involved in DNA repair mechanisms. When this enzyme is overactive or its function is compromised, it can contribute to the development and progression of various diseases, most notably certain types of cancer. Inhibiting PARP-1 activity has emerged as a promising therapeutic strategy. The synthesis of effective PARP-1 inhibitors often requires highly specific and pure chemical intermediates, making 4-Bromo-2-iodopyridine an essential component in this research.
The utility of 4-Bromo-2-iodopyridine in this field stems from its role in constructing complex molecular structures that can effectively bind to and inhibit PARP-1. Medicinal chemists employ this compound in multi-step syntheses to create novel drug candidates. The ability to modify the pyridine core at both the bromine and iodine positions allows for the fine-tuning of molecular properties, optimizing efficacy, selectivity, and pharmacokinetic profiles. For researchers actively seeking to buy 4-Bromo-2-iodopyridine for these specific applications, sourcing from a reliable manufacturer is critical.
The commitment to high purity (≥97.0%) in 4-Bromo-2-iodopyridine, as provided by NINGBO INNO PHARMCHEM CO.,LTD., ensures that the synthesis of these critical PARP-1 associated disease treatments is efficient and reproducible. The compound's physical form as a white crystal powder also indicates its quality and suitability for sensitive chemical processes. Companies investing in the development of targeted therapies for cancer and other PARP-1 related conditions will find the 4-Bromo-2-iodopyridine chemical intermediate to be an invaluable resource.
The careful handling and storage protocols for 4-Bromo-2-iodopyridine are indicative of its importance in high-stakes pharmaceutical research. By providing this crucial intermediate, NINGBO INNO PHARMCHEM CO.,LTD. supports the scientific community's efforts to combat diseases at a molecular level. Exploring how to efficiently purchase 4-Bromo-2-iodopyridine can therefore be a strategic step for organizations aiming to innovate in targeted therapy development.
In summary, 4-Bromo-2-iodopyridine is instrumental in the design and synthesis of potential treatments for PARP-1 associated diseases. Its contribution to medicinal chemistry highlights the critical role of specialized intermediates in advancing healthcare and offering new therapeutic options.
Perspectives & Insights
Silicon Analyst 88
“For researchers actively seeking to buy 4-Bromo-2-iodopyridine for these specific applications, sourcing from a reliable manufacturer is critical.”
Quantum Seeker Pro
“, ensures that the synthesis of these critical PARP-1 associated disease treatments is efficient and reproducible.”
Bio Reader 7
“The compound's physical form as a white crystal powder also indicates its quality and suitability for sensitive chemical processes.”