Benzylamine, identified by CAS number 100-46-9, is a primary organic amine with significant industrial and research applications. Its molecular formula is C7H9N, and it possesses a distinct structure featuring a benzyl group attached to an amino group. This configuration imparts unique chemical properties that make it a valuable compound across various sectors, including pharmaceuticals, agriculture, and material science. Understanding its properties, synthesis routes, and safety protocols is crucial for its effective and responsible use.

Chemically, Benzylamine is a colorless, transparent liquid with a faint ammonia-like odor. It exhibits a molecular weight of approximately 107.15 g/mol and a density of around 0.981 g/cm³. Its solubility profile is notable: it is moderately soluble in water but highly miscible with common organic solvents like ethanol, acetone, and diethyl ether. This characteristic enhances its utility in various reaction media and formulation processes. The amine group makes Benzylamine a moderately strong base, with a pKa value around 9.3, allowing it to participate in a wide range of acid-base reactions and nucleophilic substitutions.

The synthesis of Benzylamine is typically achieved through two primary industrial methods. The first involves the catalytic hydrogenation of benzonitrile (C₆H₅CN), often utilizing metal catalysts such as nickel or palladium. This route is favored for large-scale production due to its efficiency and high yields. The second common method is the reaction of benzyl chloride with ammonia, usually carried out under elevated temperature and pressure, which yields Benzylamine and ammonium chloride as a byproduct. Both methods are critical for supplying the market with this essential chemical.

When handling Benzylamine, adherence to safety guidelines is paramount. It is classified as a hazardous substance, and direct contact with skin or eyes can cause irritation or burns. Inhalation of vapors may lead to respiratory discomfort. Therefore, appropriate personal protective equipment (PPE), such as gloves, safety goggles, and lab coats, should always be worn. Adequate ventilation is also essential when working with Benzylamine. Proper storage in a cool, dry, and well-ventilated area, away from incompatible materials, is recommended. The sourcing of high-quality Benzylamine from reputable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures product integrity and safety in handling.

In conclusion, Benzylamine is a chemical compound of significant industrial importance. Its well-defined properties, accessible synthesis methods, and widespread applications make it a staple in chemical synthesis. However, its hazardous nature necessitates strict adherence to safety protocols throughout its lifecycle, from production to application and disposal.