In the precise world of pharmaceutical manufacturing, understanding the detailed specifications of chemical intermediates is not just a procedural step but a cornerstone of ensuring the quality and efficacy of the final Active Pharmaceutical Ingredient (API). (2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide (CAS: 521284-19-5), a key intermediate in the synthesis of Mirabegron, is no exception. NINGBO INNO PHARMCHEM CO.,LTD., a leading supplier from China, provides critical insights into why these specifications matter.

The physical and chemical properties of (2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide are meticulously documented to guide its application. Its appearance as a yellow powder is the first visual indicator of its identity and potential purity. Further crucial parameters include a density of 1.3±0.1 g/cm³, a high boiling point of 584.8±50.0 °C at 760 mmHg, and a flash point of 307.5±30.1 °C. These figures provide essential data for process engineers regarding handling, storage, and reaction conditions. For instance, the high boiling and flash points indicate a relatively stable compound under typical processing temperatures, reducing risks associated with volatile reactions.

Perhaps the most critical specification for any pharmaceutical intermediate is its purity, often expressed as an assay. For (2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide, the standard assay is ≥98.0%. This high purity level ensures that the intermediate is free from significant contaminants that could interfere with the synthesis of Mirabegron or introduce unwanted byproducts into the final API. NINGBO INNO PHARMCHEM CO.,LTD. places immense emphasis on achieving and maintaining this purity through advanced manufacturing and quality control processes.

Additional specifications such as residue on ignition (≤0.5%) and moisture content (≤1.0%) are also vital. Low residue on ignition indicates minimal inorganic impurities, while controlled moisture content prevents degradation or unwanted reactions that could occur if the intermediate were hygroscopic. These details are meticulously managed by NINGBO INNO PHARMCHEM CO.,LTD. to guarantee that the product delivered meets the exacting demands of pharmaceutical synthesis. The ability to buy this intermediate with such precise specifications from a reputable Chinese manufacturer provides a significant advantage for companies aiming to streamline their production and ensure the quality of their Mirabegron API.

In summary, the detailed specifications for (2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide are not merely data points but critical quality indicators. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential intermediate with the highest adherence to these specifications, supporting the pharmaceutical industry's pursuit of effective and safe medications.