Imidafenacin, identified by CAS number 170105-16-5, is a critical compound within the pharmaceutical industry, primarily serving as a key intermediate for medications treating overactive bladder (OAB). A thorough understanding of its synthesis and chemical characteristics is fundamental for manufacturers aiming to produce high-quality, effective therapeutic agents.

The journey to producing Imidafenacin is a carefully orchestrated chemical synthesis. It typically commences with the alkylation of diphenylacetonitrile. This initial step is followed by a condensation reaction with 2-methylimidazole, forming a crucial intermediate structure. The final stages involve the hydrolysis of a cyano group to a carboxamide group, often facilitated by a strong acid like 70% sulfuric acid. This multi-step process is designed to ensure the resulting compound possesses the precise molecular architecture and high purity required for pharmaceutical applications.

Chemically, Imidafenacin has the molecular formula C20H21N3O and a molecular weight of approximately 319.4 g/mol. It presents as a white solid, with a reported purity typically exceeding 98%. Its specific physical and chemical properties, such as density, boiling point, and refractive index, are detailed and closely monitored during production. These parameters are critical for process control and final product quality assurance. The chemical synthesis of Imidafenacin is a testament to the precision required in pharmaceutical intermediate manufacturing.

As a pharmaceutical intermediate, Imidafenacin's primary application is in the development of treatments for overactive bladder. Its efficacy stems from its role as a muscarinic receptor antagonist, specifically targeting M1 and M3 receptors. By antagonizing these receptors, it effectively reduces involuntary contractions of the bladder's detrusor muscle, a primary cause of OAB symptoms. Ensuring the purity of the CAS 170105-16-5 raw material is paramount; impurities can compromise the efficacy and safety of the final drug product.

The availability of Imidafenacin from various global suppliers, including companies like NINGBO INNO PHARMCHEM CO.,LTD., ensures that pharmaceutical manufacturers can secure a reliable supply. This accessibility is vital for the consistent production of OAB medications. For businesses looking to source this essential compound, understanding its chemical properties and synthesis pathway highlights why meticulous manufacturing standards are non-negotiable in the pharmaceutical sector.