Understanding the Chemical Properties of 7-Methoxy-8-Methyl-2-(4-Propan-2-yl-1,3-Thiazol-2-yl)-1H-Quinolin-4-One for Advanced Drug Synthesis
The efficacy of modern pharmaceuticals often hinges on the precise characteristics of their constituent building blocks. 7-Methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-quinolin-4-one, identified by CAS number 923289-21-8, is a prime example of such a critical component. This compound, vital for the production of Hepatitis C medications like Simeprevir, possesses a set of specific chemical and physical properties that NINGBO INNO PHARMCHEM CO.,LTD. meticulously ensures are met. Understanding these attributes is key for researchers and manufacturers working with this advanced pharmaceutical intermediate.
The compound's appearance is consistently described as a white solid, a visual indicator of its purity. Its molecular formula, C17H18N2O2S, and molecular weight of 314.402 provide the fundamental chemical identity. More importantly for synthesis, its assay of ≥99.0% signifies a high degree of purity, minimizing unwanted side reactions and ensuring the integrity of the final drug product. The low water content (≤0.5%) and sulphated ash (≤0.1%) further contribute to its suitability for sensitive pharmaceutical processes. These specifications are not merely technical details; they are critical parameters that pharmaceutical companies rely on when sourcing materials for the complex synthesis of Hepatitis C treatments. As a leading pharmaceutical intermediate supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. prioritizes these quality metrics.
Beyond purity, other physical properties of 7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-quinolin-4-one are also noteworthy. Its density of 1.2±0.1 g/cm³ and a high boiling point of 518.0±60.0 °C at 760 mmHg suggest a compound with notable thermal stability. The flash point of 267.1±32.9 °C further indicates its robustness under various processing conditions. These attributes are particularly important in multi-step chemical synthesis, where intermediates are subjected to different temperatures and environments. The exact mass of 314.108887, polar surface area (PSA) of 83.48000, and LogP of 6.12 offer deeper insights into its behavior in chemical reactions and its potential interactions within biological systems, information that is invaluable for medicinal chemists working on antiviral drug development.
The consistent adherence to these precise CAS 923289-21-8 chemical properties makes this quinoline derivative a preferred choice for pharmaceutical manufacturers. When evaluating a pharmaceutical intermediate supplier in China, the ability to consistently deliver material that meets these rigorous specifications is a key differentiator. NINGBO INNO PHARMCHEM CO.,LTD. leverages its expertise in chemical synthesis and quality assurance to provide intermediates that meet the demanding requirements of the global pharmaceutical industry. By understanding and controlling these chemical properties, NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in enabling the production of effective treatments for diseases like Hepatitis C.
In essence, the detailed understanding and control of the chemical properties of 7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-quinolin-4-one are fundamental to its application in advanced drug synthesis. These properties ensure the efficiency, safety, and ultimate success of pharmaceutical manufacturing processes, particularly for critical medications targeting widespread health challenges.
Perspectives & Insights
Chem Catalyst Pro
“In essence, the detailed understanding and control of the chemical properties of 7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)-1H-quinolin-4-one are fundamental to its application in advanced drug synthesis.”
Agile Thinker 7
“These properties ensure the efficiency, safety, and ultimate success of pharmaceutical manufacturing processes, particularly for critical medications targeting widespread health challenges.”
Logic Spark 24
“The efficacy of modern pharmaceuticals often hinges on the precise characteristics of their constituent building blocks.”