For professionals working with chemical compounds, understanding their properties and ensuring safe handling practices is paramount. 5-Chloro-2-Thiophenecarbonyl Chloride (CAS 42518-98-9) is a valuable intermediate, but like many reactive chemicals, it requires careful management. NINGBO INNO PHARMCHEM CO.,LTD. provides this essential compound with a focus on quality and safety, offering insights into its key characteristics.

Physically, 5-Chloro-2-Thiophenecarbonyl Chloride typically presents as a white powder, though some sources may describe it as a pale yellow to colorless oil depending on purity and form. Its molecular formula is C5H2Cl2OS, with a molecular weight of approximately 181.04 g/mol. Key physical properties include a melting point around 4°C and a boiling point of roughly 122-127°C at 16 Torr. It exhibits slight solubility in water and in organic solvents like chloroform and methanol. Crucially, it is noted as being moisture-sensitive and hygroscopic, meaning it readily absorbs moisture from the air. This sensitivity necessitates storage under an inert atmosphere, such as nitrogen or argon, and in tightly sealed containers, ideally refrigerated (2-8°C) to maintain its stability and reactivity.

From a safety perspective, 5-Chloro-2-Thiophenecarbonyl Chloride is classified as corrosive. Hazard statements often include indications of severe skin burns and eye damage (H314, H318). Therefore, when handling this compound, it is imperative to wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, eye protection (safety goggles or a face shield), and protective clothing. Work should be conducted in a well-ventilated area, preferably under a chemical fume hood, to avoid inhalation of any dust or vapors. In case of contact, immediate rinsing with plenty of water is essential, and medical attention should be sought promptly. Proper storage away from incompatible materials, particularly moisture, is critical to prevent decomposition and hazardous reactions. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive safety data sheets (SDS) to guide users on the safe and effective utilization of this important chemical intermediate.