Fluorinated compounds have garnered significant attention in the fields of medicinal chemistry and material science due to the unique properties conferred by the fluorine atom. In particular, fluorinated heterocycles often exhibit enhanced metabolic stability, increased lipophilicity, and altered electronic characteristics, making them valuable in drug design and synthesis. Among these, fluorinated quinazoline derivatives, such as 7-Fluoro-6-nitro-4-hydroxyquinazoline, are of considerable interest.

At NINGBO INNO PHARMCHEM CO.,LTD., we are a supplier of fine chemicals and intermediates, including this important fluorinated quinazoline. The compound 7-Fluoro-6-nitro-4-hydroxyquinazoline (CAS 162012-69-3) possesses a molecular structure that combines a quinazoline ring system with a fluorine atom and a nitro group. This specific arrangement of functional groups provides it with distinct chemical reactivity and biological potential. The fluorine atom, being highly electronegative, can influence the electron distribution within the molecule, potentially affecting binding affinities to biological targets and improving pharmacokinetic properties like bioavailability and metabolic resistance.

The nitro group, another key substituent on the quinazoline ring, can serve as a handle for further chemical transformations. It can be reduced to an amino group, which then opens up a wide array of possibilities for coupling reactions and the introduction of diverse side chains. This versatility makes 7-Fluoro-6-nitro-4-hydroxyquinazoline a crucial starting material for constructing more complex molecular scaffolds. The common specification of 7-Fluoro-6-nitro-4-hydroxyquinazoline purity at 98% ensures that synthetic chemists have a reliable reagent for their research and development activities, allowing for predictable reaction outcomes.

The applications of such fluorinated quinazoline derivatives extend across several scientific disciplines. In pharmaceuticals, as previously discussed, they are vital intermediates for drugs targeting various diseases, particularly cancers. The incorporation of fluorine into drug molecules can significantly impact their efficacy and safety profiles. Beyond pharmaceuticals, these compounds can also find use in the development of agrochemicals, dyes, and advanced materials, where their unique properties can be leveraged for specific functionalities.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to facilitating scientific progress by providing access to high-quality chemical compounds like 7-Fluoro-6-nitro-4-hydroxyquinazoline. We understand the importance of precise molecular design and reliable supply in advancing chemical synthesis and drug discovery. Our dedication to purity and quality ensures that researchers and manufacturers have the materials they need to explore the vast potential of fluorinated heterocyclic chemistry.