NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive chemical solutions, including detailed information on the synthesis and properties of key intermediates. Thiophene-3,4-dicarboxylic Acid (CAS 4282-29-5) is one such compound, vital for many industrial processes, especially in the realms of pharmaceuticals and advanced materials.

The synthesis of Thiophene-3,4-dicarboxylic Acid typically involves multi-step organic reactions. One common route starts with the oxidation of a suitably substituted thiophene precursor. For instance, thiophene-3,4-dicarbonitrile can be hydrolyzed under alkaline conditions, followed by acidification, to yield the desired dicarboxylic acid. Another approach might involve the functionalization of thiophene itself or derivatives through processes like lithiation and subsequent carboxylation. The efficiency and yield of these thiophene-3,4-dicarboxylic acid synthesis pathways are crucial for cost-effective production.

Understanding the physical and chemical properties of Thiophene-3,4-dicarboxylic Acid is essential for its effective utilization. It typically appears as a white to off-white crystalline powder. Its melting point is generally reported in the range of 227-231 °C, indicating a relatively stable solid form. The molecular formula is C6H4O4S, and its molecular weight is approximately 172.16 g/mol. The presence of two carboxylic acid groups makes it an acidic compound, capable of forming salts and undergoing esterification or amidation reactions.

Key to its industrial use is its solubility profile. While it may have limited solubility in water, it typically dissolves well in polar organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). This characteristic is important for carrying out reactions in solution and for purification processes. The CAS 4282-29-5 properties also include its potential to form stable coordination complexes with metal ions, a property leveraged in catalysis and material science.

The purity of Thiophene-3,4-dicarboxylic Acid is a critical factor for its performance in sensitive applications like pharmaceutical synthesis and the creation of high-performance electronic materials. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. focus on achieving high thiophene-3,4-dicarboxylic acid purity, often greater than 98%, through rigorous quality control measures and optimized synthesis and purification techniques.

In conclusion, Thiophene-3,4-dicarboxylic Acid is a valuable chemical intermediate whose synthesis and properties are well-understood. Its availability in high purity, coupled with its versatile reactivity, makes it an indispensable compound for advancing research and development in pharmaceuticals, organic electronics, and various material science domains.